Irvin (10-13) allowed five runs on four hits and four walks while striking out three over four innings to take the loss Sunday versus the Cubs.

Irvin yielded three home runs, which accounted for four of the five runs he surrendered. He's struggled with the Cubs both times he's faced them this year, allowing 12 runs over 8.2 innings in those starts. Irvin is now at a 4.22 ERA, 1.18 WHIP and 153:49 K:BB across 183.1 innings through 32 starts. His last start of the season is projected to be at home versus the Phillies.

Manager Carlos Mendoza said Sunday that Senga (calf) will not return from the 60-day injured list during the regular season after the right-hander felt tightness in his right tricep during a rehab outing with Triple-A Syracuse on Saturday, Will Sammon of The Athletic reports.

Senga will continue to throw, which suggests a return during the postseason may still be on the table, but he will end the regular season having made a lone appearance with the big club. The 31-year-old began the season on the IL with a shoulder strain and then strained his calf in his 2024 debut in July. His innings will be tough to project in 2025 after the injury-plagued season.

McGreevy is listed as the Cardinals' scheduled starting pitcher for Tuesday's game against the Rockies at Coors Field.

After being called up from Triple-A Memphis on Wednesday, McGreevy was put to work out of the bullpen a day later in the Cardinals' game against the Pirates. He scooped up the win while tossing three scoreless innings in relief, and he'll now get the chance to enter the St. Louis rotation for the final week of the season due to Lance Lynn (knee) and Sonny Gray (forearm) both recently going on the injured list. Unless the Cardinals elect to expand their rotation to six men by moving Steven Matz from the bullpen, McGreevy will tentatively line up for two starts during the final week of the season. After Tuesday's contest in Colorado, McGreevy would be lined up to take the hill for the finale Sunday in San Francisco.

Buehler (1-6) took the loss against the Rockies on Saturday, allowing four runs on five hits and one walk over 5.1 innings. He struck out nine.

Buehler struggled early, allowing a leadoff double to Charlie Blackmon to open the game followed by a walk to Ezequiel Tovar. The right-hander allowed one run in the frame, along with two more runs on a Tovar double in the following inning. Buehler did manage to get through five innings for the fourth consecutive start but not before allowing four or more runs for the second time in his last three outings. He now carries a 5.06 ERA in September through four starts, though his nine strikeouts Saturday did mark a season high for the 30-year-old.

Fried (10-10) picked up the win Saturday, allowing two runs (one earned) on five hits and a walk over six innings in a 6-2 victory over the Marlins. He struck out six.

The lefty delivered his second straight quality start and fourth in his last five outings on 100 pitches (69 strikes), but Fried left the mound with the score tied 2-2 before Atlanta's offense erupted in the top of the seventh to get him the win. Over his last eight trips to the mound, Fried has posted a 3.10 ERA, 1.09 WHIP and 47:13 K:BB through 49.1 innings. With Atlanta trying to catch the Mets for the final wild-card spot in the NL, his final outing of the regular season could be a big one -- it comes at home next weekend against the Royals.

Quantrill did not factor into the decision against the Dodgers on Saturday, allowing three runs on six hits and four walks over 4.2 innings while striking out five.

Quantrill retired eight of the first nine batters he faced before allowing a walk to Shohei Ohtani followed by a two-run shot off the bat of Mookie Betts. The right-hander then surrendered a third run in the fourth and did not make it through the fifth after reaching 100 pitches. Quantrill has now issued four or more walks in three consecutive starts and at least two walks in nine straight. He's also winless over his last four starts, surrendering multiple runs in each of those outings, and hasn't gotten through six innings since July 24 against the Red Sox (a span of seven starts).

Greene (elbow) was activated from the 15-day injured list ahead of his scheduled start Sunday against the Pirates.

The first-time All-Star will return for his first start since Aug. 13, having completed a 52-pitch simulated game Tuesday. Greene will likely be on a short leash in his final two starts of the season, as the Reds prioritize keeping him healthy heading into the winter. Alan Busenitz was designated for assignment in a corresponding move.

Manaea (12-5) picked up the win in Saturday's 6-3 victory over the Phillies, giving up three runs on three hits over seven innings. He struck out six without walking a batter.

Solo shots by Kyle Schwarber to lead off the game and Nick Castellanos in the fifth inning accounted for most of the damage off Manaea, but he was otherwise locked in as he won his fourth straight decision. The quality start was the southpaw's third straight and seventh in his last eight outings, a stretch in which he's posted a 2.95 ERA, 0.67 WHIP and 58:10 K:BB through 55 innings. Manaea is scheduled to make his final start of the regular season on the road next week against Atlanta -- the team closest to the Mets in the race for the final wild-card spot in the NL.

Suarez came away with a no-decision in Saturday's 6-3 loss to the Mets, giving up two runs on five hits and three walks over five innings. He struck out four.

The southpaw exited the mound after 91 pitches (57 strikes) with the score tied 2-2, and both New York runs came on second-inning solo shots by Francisco Alvarez and Luisangel Acuna. Suarez hasn't completed six innings in a start since the All-Star break, and his last quality start came back on June 25. In six starts since returning from back trouble in late August, he's posted a 4.30 ERA, 1.53 WHIP and 27:12 K:BB through 29.1 innings. He lines up to make his last start of the regular season on the road next weekend against the Nationals, but with the Phillies having clinched the NL East, they could shuffle things around to set up their postseason rotation.

Perez (5-5) picked up the win over the White Sox on Saturday, allowing one run on two hits and three walks over 5.1 innings. He struck out six.

Perez retired seven of the first eight batters he faced before issuing two free passes in the top of the third. The veteran right-hander was able to work his way out of the jam, however, and allowed just one run through five frames before again running into trouble in the sixth. Perez would then be relieved by Bryan Hoeing with one out in the inning, though the former was still able to log his fifth win of the campaign and his third as a member of the Padres. He's now allowed one run or fewer in each of his last three starts and carries a very strong 1.08 ERA in September to go along with a 13:5 K:BB.