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Jacob Misiorowski SP | MIL
Brewers' Jacob Misiorowski: Fans 11 in dominant opening start
Misiorowski (1-0) earned the win Thursday against the White Sox, allowing one run on two hits and three walks while striking out 11 over five innings.
The 23-year-old was electric on Opening Day, piling up 25 whiffs on 94 pitches while leaning heavily on his fastball, throwing it 61 times. Misiorowski's only blemish came on a leadoff home run, but he quickly settled in and dominated from there, striking out eight of the next 12 batters. After breaking onto the scene with a strong finish to last season, posting a 4.36 ERA, 1.24 WHIP and 87 strikeouts across 66 regular-season innings, the right-hander looks to be picking up right where he left off.
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Marcelo Mayer 3B | SF
Red Sox's Marcelo Mayer: Impacts win off bench
Mayer entered Thursday's game as a pinch hitter and went 2-for-2 with a double and a run scored in a 3-0 win over Cincinnati. He finished the game at second base.
Mayer was held out of the starting lineup against a lefty but got his chance after Reds starter Andrew Abbott was removed. Pinch hitting for Isiah Kiner-Falefa, Mayer led off the seventh inning with a double and scored the game's first run. He later led off the ninth with a single that triggered a two-run frame. Red Sox manager Alex Cora plans a three-player platoon at second base with Mayer against righties, while Kiner-Falefa and Andruw Monasterio handle southpaws. Mayer should get his first start Saturday against Reds' right-hander Brady Singer.
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Roman Anthony LF | BOS
Red Sox's Roman Anthony: On base four times
Anthony batted leadoff and went 3-for-4 with a walk and a run scored in Thursday's 3-0 victory over the Reds.
None of Anthony's three hits impacted the final score, but his ABS challenge in the top of the ninth inning turned a potential inning-ending strikeout into a walk. Two batters later, he came around to score as the Red Sox added two insurance runs. Anthony is expected to bat leadoff this season and could be among the league leaders in plate appearances.
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Ben Brown RP | CHC
Cubs' Ben Brown: Mops up innings Opening Day
Brown allowed two runs on three hits across 3.1 innings in Thursday's 10-4 loss to the Nationals. He walked one and struck out three.
The righty reliever was forced into early action after Chicago starter Matthew Boyd covered only 3.2 innings in a rough outing. Brown served up a two-run home run to Jacob Young to account for the runs against him. After making 23 regular-season starts for the Cubs across the last two seasons, it looks like Brown will handle a long-relief role out of the bullpen in 2026. He should be a decent source of strikeouts, though his overall fantasy value will be capped as a reliever.
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Dillon Dingler C | DET
Tigers' Dillon Dingler: Tees off Opening Day
Dingler went 2-for-5 with a home run and three RBI in Thursday's 8-2 win over the Padres.
Dingler got off to a slow start in camp following arthroscopic right elbow surgery in the offseason, but he heated up toward the end of Grapefruit League play and carried that momentum into Opening Day. The 27-year-old is expected to see the bulk of the playing time behind the plate for the Tigers, and after an encouraging 2025 regular season that saw him club 13 homers with a .752 OPS, Dingler could be in store for bigger and better things in 2026.
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Kevin McGonigle SS | DET
Tigers' Kevin McGonigle: Tallies four hits in MLB debut
McGonigle went 4-for-5 with two doubles, two RBI and two runs scored in Thursday's 8-2 win over the Padres.
Making his MLB debut, McGonigle started at third base and batted sixth Opening Day, and he made quite the first impression on the heels of a strong spring training. The youngster became just the second Detroit player ever to record four hits in his first game in the majors. McGonigle is expected to see plenty of time at shortstop this year, though he covered the hot corner Thursday with Javier Baez starting at short. No matter where McGonigle plays in the field, he looks ready to make a fantasy impact right away.
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Andrew Abbott SP | CIN
Reds' Andrew Abbott: Turns around rough spring
Abbott allowed seven hits and one walk while striking out four over six scoreless innings, picking up a no-decision in Thursday's 3-0 loss to Boston.
Abbott pitched in and out of trouble in three of his innings, but he matched zeros with Boston's Garrett Crochet on the scoreboard. The seven hits off the Reds' left-hander were all singles, four of which didn't leave the infield. It was an encouraging outing for Abbott, who had a shocking 11.72 ERA in spring training. He's become the team's No. 1 starter with Hunter Greene (elbow) unavailable and on the 60-day injured list.
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Pete Crow-Armstrong CF | CHC
Cubs' Pete Crow-Armstrong: Drives in two Opening Day
Crow-Armstrong went 2-for-5 with two RBI in Thursday's 10-4 loss to the Nationals.
The Cubs put Crow-Armstrong in the cleanup spot Opening Day, and he responded with a team-best two RBI. After a breakout 2025 campaign, the young outfielder inked a six-year, $115 million contract extension earlier this week. Crow-Armstrong did fade some down the stretch last year, however, which is something he will aim to avoid in 2026. He made some minor mechanical tweaks in the offseason in an effort to make his swing more compact and find a bit more consistency at the plate across the long season.
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Michael Busch 1B | CHC
Cubs' Michael Busch: Tallies three hits in opener
Busch went 3-for-4 with a walk, two doubles, an RBI and two runs scored in Thursday's 10-4 loss to the Nationals.
Like he did much of last season, Busch hit leadoff Opening Day, and the Chicago first baseman picked up right where he left off after an impressive 2025 campaign. Busch batted first with Washington starting righty Cade Cavalli, and the Cubs have said the left-handed bat won't be deployed strictly in a platoon, so he should have plenty of opportunities against southpaws moving forward.
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Sal Stewart 1B | CIN
Reds' Sal Stewart: Rips three hits in opener
Stewart batted cleanup and went 3-for-4 with two doubles in Thursday's 3-0 loss to the Red Sox.
Reds manager Terry Francona began experimenting with Stewart batting fourth followed by Eugenio Suarez late in spring training and stuck with it for Opening Day against Boston left-hander Garrett Crochet. The 22-year-old Stewart collected three of the four hits Boston's ace would allow, and Stewart managed to stay in the game after taking a Roman Anthony line drive off the hand while playing the field. Stewart slashed .327/450/.592 during spring training with four doubles, three home runs and 11 RBI across 20 games and will be the Reds' mainstay at first base and part of the rotation at DH, but he could also be an option at second or third base.