Enright (elbow) was designated for assignment by the Guardians on Tuesday, Zack Meisel of The Athletic reports.

Enright loses his 40-man spot on Rule 5 deadline day after undergoing Tommy John surgery shortly after the end of the 2025 regular season. He will miss all of 2026, but Enright showed real promise before going down with a 2.03 ERA and 1.16 WHIP over 31 innings out of the Cleveland bullpen, numbers which may attract a team on the other end of the competitive spectrum.

The Orioles designated Leon (knee) for assignment Tuesday.

The 27-year-old was claimed off waivers by Baltimore earlier in November but is already off the 40-man roster. Leon spent the 2025 season on the injured list due to knee issues, though he did play in 25 rehab games in the minors.

The Cubs selected Ramirez's contract from Double-A Knoxville on Tuesday.

Ramirez is unlikely to compete for a big-league job in spring training, given that he has never played at Triple-A. However, the 21-year-old switch hitter is a good athlete capable of playing multiple infield positions. Ramirez slashed .280/.346/.386 with eight home runs, 28 steals and a 15.1 percent strikeout rate in 129 games at Double-A in 2025, good for a 118 wRC+.

The Red Sox traded Bernardino (lat) to Colorado on Tuesday in exchange for Braiden Ward, Patrick Saunders of The Denver Post reports.

Bernardino enjoyed a strong 2025 season with Boston, posting a 3.14 ERA, 1.26 WHIP and 43:26 K:BB over 51.2 innings while notching one save and two holds. The southpaw ended the campaign on the IL due to a strained lat, but there's no reason at this point to think that the injury will affect his availability for the start of spring training. Bernardino should immediately become a key member of a Rockies bullpen that ranked second-to-last in the majors with a 5.18 ERA last year.

Rainey was designated for assignment by the Tigers on Tuesday, Cody Stavenhagen of The Athletic reports.

Rainey's relevance in the fantasy world was fleeting, as he quickly fell off the map after the 2020 season. He has bounced from Washington to Pittsburgh to Detroit in recent years while mostly struggling on the mound. He pitched to an ugly 11.17 ERA and 1.76 WHIP over 9.2 major-league innings in 2025.

The Orioles selected Foster's contract from Triple-A Norfolk on Tuesday.

The 26-year-old was acquired from the Mets in the Gregory Soto trade over the summer, so his addition to the 40-man roster was to be expected. Foster pitched in 13 games for Triple-A Norfolk after the trade and had a 3.38 ERA, 1.38 WHIP and 23:8 K:BB over 16 innings.

The Cardinals designated Alcala for assignment Tuesday, John Denton of MLB.com reports.

Alcala struggled to find his footing on the mound in 2025, finishing the regular season with a 6.22 ERA and 1.75 WHIP across 55 total innings between Minnesota, Boston and St. Louis. He'll have the right to elect free agency if he clears waivers, although he will likely have to settle for a minor-league deal if he does so.

The Phillies selected Rincones' contract from Triple-A Lehigh Valley on Tuesday.

Rincones is one of Philadelphia's top prospects, so it's no surprise the organization elected to protect him from being taken during the upcoming Rule 5 Draft. In his first taste of the Triple-A level in 2025, the 24-year-old posted a .242/.366/.430 slash line with 18 homers and 22 steals in 119 games.

The Tigers designated Mattison for assignment Tuesday, Cody Stavenhagen of The Athletic reports.

Mattison was added to the 40-man roster last November, but he finds himself on the other side of Rule 5 cutdown day this time around. The right-hander has yet to make his major-league debut. He pitched mostly between Double-A and Triple-A this past season after recovering from right UCL reconstruction surgery.

The Cardinals selected Hjerpe's (elbow) contract from Double-A Springfield on Tuesday, John Denton of MLB.com reports.

Hjerpe is expected to miss the first portion of the 2026 season after undergoing Tommy John surgery in April, but the Cardinals will grant him a 40-man spot anyway to ensure he doesn't get selected by another club during the Rule 5 Draft. The 24-year-old lefty owns a 3.38 ERA and 1.18 WHIP across his minor-league career and will presumably return to Double-A once he's deemed fully healthy.