Mariota completed 16 of 27 passes for 156 yards and two touchdowns with one interception in Sunday's 34-27 loss to the Falcons. He added 20 rushing yards on two carries. He also threw a two-point conversion to Zach Ertz.

Making his second straight start in place of Jayden Daniels (knee), Mariota and the Commanders' offense started slowly but eventually caught fire, only for the team's defense to be unable to come up with a stop when it needed one. Mariota tossed a five-yard TD to Luke McCaffrey late in the second quarter and a 24-yard score to Deebo Samuel in the fourth, while also leading three drives that ended in field goals in the second half. Daniels appears to be on track to return in Week 5, but if Mariota needs to take the reins again, he'll get a tough road matchup against the Chargers.

Rodgers completed 18 of 22 passes for 200 yards, one touchdown and no interceptions in Sunday's 24-21 win over the Vikings. He added three rushes for eight yards.

The Steelers played from ahead for most of the game, so Rodgers attempted only eight passes in the second half. He managed to move the offense efficiently when asked, however, with the key to his day being an explosive 80-yard touchdown to DK Metcalf early in the second quarter. This was a return to form for Rodgers, as he had only a 3:3 TD:INT while combining to throw for 332 yards across his last two games. Pittsburgh is likely to continue to rely on its run game and short passes to move the offense, which will lead to inconsistent fantasy results for Rodgers.

Leonard (coach's decision) is inactive for Sunday's game against the Rams but will serve as the Colts' emergency third-string quarterback.

Leonard has been Indy's emergency third-string quarterback for every game so far this season. He will only be eligible to enter the game if both Daniel Jones and Anthony Richardson are forced out due to injury, illness or ejection.

Jones (knee) is active for Sunday's contest against the Jaguars, Briana Jeannel of the 49ers' official site reports.

Jones emerged from his second consecutive start in place of Brock Purdy (left shoulder/toe) last Sunday against the Cardinals with a sprained PCL in his left knee. The issue limited Jones' practice reps this week, and he entered the weekend listed as questionable, while coach Kyle Shanahan announced Purdy as the 49ers' starting QB on Friday. When the team didn't elevate practice-squad member Adrian Martinez on Saturday, it signaled that Jones was in line to serve as Purdy's backup, which now has been confirmed.

Wentz completed 30 of 46 passes for 350 yards and two touchdowns with two interceptions in Sunday's 24-21 loss to the Steelers in Dublin. He added 12 rushing yards on two carries and also threw a two-point conversion to Jalen Nailor.

The Vikings lost right tackle Brian O'Neill to a knee injury and center Ryan Kelly to a concussion in the first half, and Wentz was under constant pressure as a result, getting sacked six times in total. Minnesota headed into the fourth quarter staring at a 21-6 deficit, but Wentz was able to lead a comeback that fell just short, hitting Zavier Scott for a 16-yard TD and Nailor for a two-yard score inside the final four minutes. On the other hand, the veteran QB almost threw a third INT in crunch time, only to have it overturned upon review. With J.J. McCarthy (ankle) not quite 100 percent yet, Wentz is expected to get another start in London for a Week 5 clash with the Browns, but he'll need to take better care of the ball to have a shot at retaining the job when the Vikings return from Europe.

Winston (coach's decision) is listed as inactive but available as the Giants' emergency third quarterback Sunday versus the Chargers, Dan Salomone of the Giants' official site reports.

While Winston will retain his role from the first three games of the season, the top of New York's QB depth chart has changed Week 4, with Jaxson Dart poised for his first NFL start and Russell Wilson handling backup duties. Winston will see the field only if Dart and Wilson suffer injuries.

DeVito (coach's decision) is the Patriots' inactive emergency third QB for Sunday's game against the Panthers.

In that context, Joshua Dobbs will continue to serve as Drake Maye's top backup in Week 4. Look for DeVito to remain the team's emergency No. 3 QB as long as Maye and Dobbs both remain healthy.

Howell (coach's decision) is inactive but available as the Eagles' emergency third quarterback Sunday in Tampa Bay.

Howell served as Philadelphia's backup signal-caller to Jalen Hurts in the first three games of the season with Tanner McKee recovering from a broken thumb. Now that McKee can handle the No. 2 role, Howell will move to No. 3 and only see if the field if both Hurts and McKee leave Sunday's contest due to injury.

Mayfield (right biceps) is listed as active Sunday against the Eagles.

Mayfield operated with a cap on his reps during Week 4 prep due to a right biceps injury and wasn't seen throwing passes until Friday's practice. Despite entering the weekend as questionable, he'll lead the Buccaneers offense as he normally does Sunday, with Chris Godwin (foot) swapping in for an absent Mike Evans (hamstring) at wide receiver. Godwin is making his season debut after completing his recovery from the dislocated left ankle that he suffered Week 7 of the 2024 campaign, so he may not be running on all cylinders for at least a few games. In any case, Mayfield's top available skill-position talents will be RB Bucky Irving, WRs Godwin, Emeka Egbuka and Sterling Shepard and TE Cade Otton.

Daniels (knee) will remain out for Sunday's game in Atlanta but is expected to return to action in the Commanders' Week 5 road matchup with the Chargers on Oct. 5, Ian Rapoport of NFL Network reports.

Daniels turned in a pair of limited practices this week, but the Commanders are opting to hold the second-year signal-caller out for a second straight game while he manages a knee sprain. Though Marcus Mariota will once again start for Washington, Daniels' knee responded well to a workout Saturday, leaving the Commanders optimistic that the 24-year-old will be ready to go next week for a tough matchup with the undefeated Chargers. Whether Daniels enters the Week 5 contest with or without an injury designation will hinge on his practice activity next Wednesday through Friday.