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Justin Herbert QB | LAC
Chargers' Justin Herbert: Fails to produce TD in Week 6 loss
Herbert completed 22 of 37 passes for 204 yards, no touchdowns and one interception in Sunday's 22-6 loss to the Chiefs. He also rushed five times for 26 yards.
Herbert continued to struggle but once again got little help from his teammates. Top wide receiver Ladd McConkey (concussion) exited early and the Chargers couldn't generate much on the ground, as Herbert led the team in rushing yards. Herbert was held without a touchdown for the first time this season after throwing exactly one touchdown pass in each of the previous five games. The 0-6 Chargers are the first team to six losses this season, as the Titans notched their first win of the season over the Colts on Sunday to improve to 1-5, while the winless Dolphins were on bye. Herbert will be on bye in Week 7 before his next opportunity to snap this season-opening losing streak in a nominal road game against the Rams in Week 8.
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Tyler Shough QB | NO
Saints' Tyler Shough: Four TDs in Week 6 win
Shough completed 16 of 30 passes for 144 yards and three touchdowns in Sunday's 34-27 win over the Giants. He added 32 yards and a TD on five carries.
While he didn't produce much yardage, Shough kept the Saints' offense humming, connecting with Bryce Lance, Alvin Kamara and Chris Olave for scores through the air while adding a one-yard touchdown on the ground in the third quarter. Shough has been playing through a couple broken bones in his non-throwing hand, which could help explain why he has just 242 passing yards over the last two weeks, but the second-year QB showed he can be plenty productive despite the injury. Shough will take a 12:5 TD:INT through six games into a Week 7 tilt against the Steelers in Paris.
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Jacoby Brissett QB | ARI
Cardinals' Jacoby Brissett: Beats Rams despite dearth of TDs
Brissett completed 24 of 35 passes for 218 yards, no touchdowns and one interception in Sunday's 18-16 win over the Rams. He also rushed twice for two yards.
Brissett was held without a touchdown pass for the first time this season, but he did enough to lead the Cardinals into field-goal range six times, and Arizona's defense and special teams delivered an inspired performance to pull off an unlikely road win over the NFC West rival Rams. Both of Brissett's wins this season have come at SoFi Stadium, as he also defeated the Chargers in LA in Arizona's regular-season opener. Brissett will try to notch his first home win of the season in Week 7 against the Broncos while attempting to improve his 9:6 TD:INT through six games.
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Daniel Jones QB | IND
Colts' Daniel Jones: Picked off twice in rough Week 6 loss
Jones completed 22 of 42 passes for 269 yards and a touchdown with two interceptions in Sunday's 26-20 loss to the Titans.
The Colts committed three turnovers in total and also had a blocked punt returned for a touchdown in an ugly loss to the previously winless Titans. Through six games this season, Jones carries a 4:6 TD:INT and career-worst 5.9 YPA as he struggles to find last year's form, but a depleted group of pass catchers that saw tight end Tyler Warren (groin) sidelined as well Sunday may be contributing to Jones' woes. He's unlikely to find a rhythm in Week 7 against the Vikings' stingy defense.
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Cam Ward QB | TEN
Titans' Cam Ward: Quiet in Week 6 win
Ward completed 11 of 22 passes for 102 yards and one touchdown with one interception in Sunday's 26-20 win over the Colts. He added seven yards on three carries.
The second-year QB put together his least productive game of the season, but Ward did connect with Carnell Tate for an eight-yard score in the fourth quarter. The Titans' special teams units accounted for the rest of their points in the team's first win of the year on four Joey Slye field goals and a blocked punt return for a TD. Ward has failed to reach 200 passing yards in five of six games to begin the season with a 4:4 TD:INT, giving him little fantasy appeal heading into a Week 7 tilt against the Browns.
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Aidan O'Connell QB | LV
Raiders' Aidan O'Connell: Emergency QB for Week 6
O'Connell (coach's decision) is inactive but will serve as the Raiders' emergency third quarterback against the Bills on Sunday.
O'Connell remains the third option behind Kirk Cousins and Fernando Mendoza. The quarterback will only enter the game if both Cousins and Mendoza must leave the contest due to injury, illness or ejection.
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Ty Simpson QB | LAR
Rams' Ty Simpson: Emergency QB for Week 6
Simpson (coach's decision) is inactive but will serve as the Rams' emergency third quarterback against the Cardinals on Sunday.
As the inactive emergency third option, Simpson cannot play in Sunday's contest unless both Matthew Stafford and Stetson Bennett leave the game due to injury, illness or ejection.
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Carson Beck QB | ARI
Cardinals' Carson Beck: Emergency QB once again
Beck (coach's decision) is inactive and is designated as Arizona's emergency third quarterback for Sunday's matchup versus the Rams, Darren Urban of the Cardinals' official site reports.
Beck remains the third option behind Jacoby Brissett and Gardner Minshew. The rookie third-rounder will only enter Sunday's contest if both Brissett and Minshew are unable to continue playing.
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Michael Penix Jr. QB | ATL
Falcons' Michael Penix: Returns to game Sunday
Penix (undisclosed) reentered Sunday's game versus the Bears, Will McFadden of the Falcons' official site reports.
Penix paid a visit to the sideline tent in the first quarter of Week 6 action, but after a spell on the bench he was able to check back into the contest. If Penix eventually does miss any snaps, Tua Tagovailoa is on hand to direct the Falcons offense.
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Trevor Lawrence QB | JAC
Jaguars' Trevor Lawrence: Launches four TDs in London loss
Lawrence completed 24 of 41 passes for 306 yards and four touchdowns with one interception in Sunday's 34-31 loss to the Texans. He added 11 rushing yards on three carries.
The Jaguars had to open things up in the second half after falling behind 24-14 following the Texans' first possession of the third quarter, and Lawrence wound up attempting 40-plus passes for the first time this season while tying his 2026 high in TD passes with two scores to Bhayshul Tuten, and one each to Travis Hunter and rookie tight end Nate Boerkircher. He also topped 300 passing yards for a second straight game. Lawrence will take a 14:4 TD:INT into a bye before clashing with the Colts in Week 8.