Perine (ankle) is inactive for Sunday's game against the Patriots.

Listed as doubtful heading into Sunday after failing to practice in any fashion this week, Perine will unsurprisingly wind up missing a second straight game. His absence will clear the way for Tahj Brooks to serve as the No. 2 running back behind starter Chase Brown, who should continue to see increased involvement on passing downs sans Perine.

Walker (glute) is active for Sunday's game against the Titans.

Head coach Mike Macdonald expressed optimism that Walker would suit up and reports earlier in the weekend suggested the same. Walker's status is now official after he popped up on the injury report Friday. It's unclear whether his workload will be affected, as Zach Charbonnet has cut significantly into Walker's opportunities even when Walker has been fully healthy.

Stevenson (toe) is listed as active for Sunday's game against the Bengals.

Stevenson, who last appeared in a game in Week 8, was limited at practice Wednesday and Thursday, but the running back's full participation in Friday's session foreshadowed his active status Sunday. Stevenson is thus slated to rejoin a backfield that also includes rookie second-rounder TreVeyon Henderson, who combined for five total TDs over New England's last two contests. Prior to missing three straight weeks of action, Stevenson logged 83 carries for 279 yards and three TDs, while adding 16 catches (on 19 targets) for 169 yards in eight games. In his return to action versus Cincinnati, Stevenson should reclaim his key role in the Patriots' ground game, though in terms of volume it's possible that Henderson factors in more than he did the last time the two backs were both available.

Jacobs (knee) is inactive for Sunday's game against the Vikings, Mike Spofford of the Packers' official site reports.

Jacobs made an early exit from a Week 11 win at the Giants with what he eventually called a bone bruise in his knee and a thigh contusion, per Wes Hodkiewicz of the Packers' official site. After opening Week 12 prep with no activity Wednesday, Jacobs followed it up with back-to-back limited practices and entered the weekend as questionable. Adam Schefter of ESPN reported Saturday evening that Jacobs was slated to go through a pregame warmup before Green Bay made a decision on his availability, and the team didn't see enough to clear him for Sunday's contest. Emanuel Wilson thus is set to pace the Packers backfield for at least one game, while Chris Brooks and practice-squad elevation Pierre Strong also are on hand for RB reps. Jacobs will turn his focus to a Thanksgiving Day matchup at Detroit.

Jacobs (knee) isn't expected to play Sunday against the Vikings, Tom Pelissero of NFL Network reports.

Adam Schefter of ESPN reported Saturday evening that Jacobs' availability for Week 12 would come down to a pregame warmup, but even before the running back could partake in one, the Packers seem to be leaning toward giving him the day off due to the bone bruise in his knee and thigh contusion that he sustained last Sunday at the Giants. Green Bay's inactive list will be confirmed about 90 minutes before Sunday's 1:00 p.m. ET kickoff, but assuming Jacobs' name is included, Emanuel Wilson will be lined up to be the team's No. 1 RB, with Chris Brooks and practice-squad elevation Pierre Strong also on hand.

Walker (glute), who is questionable for Sunday's matchup against Tennessee, is expected to suit up, Adam Schefter of ESPN reports.

Schefter's report aligns with what Seattle head coach Mike Macdonald previously said Friday, when he intimated that Walker was in line to play Sunday despite dealing with a glute injury. Though Walker is expected to be formally cleared when the Seahawks release their inactive list 90 minutes prior to Sunday's 1 p.m. ET kickoff, it's unclear if the glute issue will result in him ceding more snaps to fellow tailback Zach Charbonnet. As it is, Walker and Charbonnet have been working in a fairly even timeshare for most of the season. During last week's loss to the Rams, Walker tallied 42 offensive snaps to Charbonnet's 36, though Walker was far more productive with 111 yards from scrimmage to Charbonnet's 47.

Irving (shoulder/foot), who has been ruled out for Sunday's game against the Rams, is expected to return to action Week 13 versus Arizona, Adam Schefter of ESPN reports.

Schefter notes that Irving "looked strong" in practice this week and may have been able to play Sunday, but the Buccaneers ultimately elected to hold him out. Assuming Irving continues to make positive progress in practice during the upcoming week, he should be on track to return to action against the Cardinals and bring an end to an absence that will have spanned seven games. Irving had been Tampa Bay's clear lead back before getting hurt, and he totaled 165 yards from scrimmage (102 receiving, 63 rushing) in the final game prior to his absence. Rachaad White and Sean Tucker have been serviceable in Irving's absence, but Irving should eventually regain the lead-back role once he's closer to 100 percent. However, he could be eased in a bit in his first game back.

Kamara (ankle), who is officially questionable for Sunday's game against Atlanta, is expected to play, Adam Schefter of ESPN reports.

Kamara has been dealing with a lingering ankle issue since early October, but the issue hasn't yet cost him any time. Following New Orleans' Week 11 bye, Kamara logged a trio of limited practices this week and again seems likely to play Sunday. He should continue to lead the Saints backfield, with rookie Devin Neal serving as the team's No. 2 running back.

Stevenson, who is officially questionable for Sunday's matchup against Cincinnati due to a toe injury, is expected to suit up, Adam Schefter of ESPN reports.

The toe issue caused Stevenson to miss each of New England's past three games. During that time, rookie running back TreVeyon Henderson moved into the No. 1 role and scored five touchdowns (four rushing, one receiving) while averaging 88.0 rushing yards and 22.0 receiving yards per contest. With that in mind, Stevenson -- who logged offensive snap shares north of 70 percent in each of the three games prior to his absence -- may be part of a more even timeshare out of the backfield if he's cleared to play ahead of Sunday's 1 p.m. ET kickoff.

The Chiefs elevated Edwards-Helaire from the practice squad to the active roster Saturday, Nick Jacobs of KSHB 41 in Kansas City reports.

Edwards-Helaire will offer added depth to the running back position, as starter Isiah Pacheco (knee) is out for Week 12 against the Colts. The 2020 first-round pick will likely be active behind Kareem Hunt, Elijah Mitchell and Brashard Smith.