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Cam Akers RB | SEA
Rams' Cam Akers: Time in L.A. may be over
Akers (personal), who is listed as out for Sunday's game against the Panthers, may have played his last down in Los Angeles, as the Rams are expected to field trade offers on the running back, Ian Rapoport of NFL Network reports.
Akers was absent from practices Thursday and Friday before being ruled out for the Week 6 game, and Rapoport relays that the 23-year-old's decision to step away from the team stemmed from philosophical and football-related differences with head coach Sean McVay. Sources tell Rapoport that the relationship between player and coach has remained cordial, so the possibility exists that Akers may be able to put aside his differences with the Rams and resume playing for the team if a trade suitor can't be found. The belief is that Akers will draw significant trade interest, however, despite his struggles to regain explosiveness as a ball carrier since he suffered a torn Achilles' tendon in July 2021. At least for Week 6 and likely beyond, Darrell Henderson is expected to serve as the Rams' clear top running back, with Malcolm Brown and Ronnie Rivers providing depth behind him.
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Gus Edwards RB | LAC
Ravens' Gus Edwards: Not activated for Week 6
Edwards (knee) wasn't activated from the PUP list ahead of Sunday's game against the Giants, Jonas Shaffer of The Baltimore Sun reports.
Per Jeff Zrebiec of The Athletic, coach John Harbaugh indicated Friday that Edwards is getting close to a return, but at this stage the running back isn't quite ready to make his season debut. With Justice Hill (hamstring) listed as doubtful, look for Kenyan Drake and Mike Davis to work behind J.K. Dobbins versus New York on Sunday.
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Damien Harris RB | BUF
Patriots' Damien Harris: True game-time decision
Harris (hamstring), who is listed as questionable for Sunday's contest against the Browns, will work out prior to 1 p.m. ET kickoff before the Patriots determine his availability, Ian Rapoport of NFL Network reports.
Harris appears to be a true game-time decision, so fantasy managers may not have confirmation of his status until New England posts its inactive list 90 minutes prior to kickoff. Previous reports have suggested that Harris' hamstring issue would force him to miss time, but the Patriots are giving him a chance to prove his health. If Harris were to sit out against Cleveland or is available only in a limited capacity, Rhamondre Stevenson would likely take on a lead role in New England's backfield.
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Latavius Murray RB | BUF
Broncos' Latavius Murray: No designation for Monday
Murray (wrist) doesn't have a designation for Monday's game at the Chargers.
On Oct. 3, the Broncos signed Murray of the Saints' practice squad in the wake of Javonte Williams' torn ACL, but he was a healthy scratch for the team's last game Thursday, Oct. 6, likely due to his lack of familiarity with the playbook. After logging full practices throughout Week 6 prep, though, Murray is ready for his Denver debut. With Melvin Gordon (neck/ribs) questionable, there's a chance Mike Boone and Murray may be more involved out of the backfield, assuming the latter is active.
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Malik Davis RB | DAL
Cowboys' Malik Davis: Rejoins roster
Dallas elevated Davis from the practice squad to its active roster Saturday ahead of Sunday's game at the Eagles.
With Rico Dowdle (ankle) headed to the injured reserve list, Davis will now serve as the Cowboys' third running back. The 23-year-old back has not seen NFL game action yet, but he produced well as a rusher at Florida.
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Alexander Mattison RB | MIA
Vikings' Alexander Mattison: Likely to play
Mattison (shoulder), officially listed as questionable for Sunday's game against the Dolphins, is expected to play, Jeremy Fowler of ESPN.com reports.
Mattison logged limited practices all week after suffering the injury in Minnesota's Week 5 win over Chicago. He earned a season-high 12 touches in that game but could see his workload scaled back in Week 6, given that he's nursing the shoulder injury along with the fact that Dalvin Cook is further removed from his own dislocated left shoulder, which he suffered Week 3. Mattison's status will become official when Minnesota releases its inactive list 90 minutes prior to Sunday's 1 p.m. ET kickoff.
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Ronnie Rivers RB | LAR
Rams' Ronnie Rivers: Suiting up vs. Carolina
The Rams elevated Rivers from the practice squad to their active roster Saturday ahead of Sunday's game versus the Panthers.
Rivers will make his NFL debut in Week 6 with regular starting running back Cam Akers (personal) out. The rookie is small (5-foot-9, 195 pounds) and slow (4.60-second 40) by NFL standards, but he showed some ability as a pass catcher at Fresno State.
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Melvin Gordon RB | BAL
Broncos' Melvin Gordon: Questionable for Monday
Gordon (neck/ribs) is listed as questionable Monday's contest against the Chargers, Jeff Legwold of ESPN.com reports.
It seems as if Gordon has a decent shot at playing in the pivotal divisional contest given the veteran practiced at limited capacity all week, but the team will likely have more information available throughout the weekend. The 29-year-old should be primed for a positive fantasy outing if he's able to play, considering the Chargers have allowed 100-yard rushers in three consecutive games.
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D'vonte Price RB | IND
Colts' D'Vonte Price: Joins active roster for Week 6
Indianapolis elevated Price from the practice squad to its active roster Saturday ahead of Sunday's game versus Jacksonville.
Price will likely suit up for his first NFL game Sunday. The undrafted rookie out of Florida International has a skinny build for a running back, but he flashed exceptional speed at the combine (4.38-second 40) and was very effective as a rusher in college.