McCaffrey (calf) remains listed as questionable but is expected to play in Sunday's season opener against the Seahawks, Adam Schefter of ESPN reports. "He's good to go," one source told Schefter.

Fantasy managers will still want to confirm that McCaffrey is suiting up when the 49ers release their inactive list 90 minutes prior to Sunday's 4:05 p.m. ET kickoff, but the running back looks on track to play through the calf issue, which resulted in him being limited in Thursday's practice before he worked out off to the side during Friday's session. According to Ian Rapoport of NFL Network, McCaffrey was a "big participant" in Saturday's team walk-through, which suggests that the running back will be in line to fill his usual duties as the 49ers' lead back Sunday.

Judkins won't be activated for Sunday's game against the Bengals, but the Browns are optimistic that the rookie running back will be ready to make his NFL debut next weekend in Baltimore, Adam Schefter of ESPN reports.

Judkins finally put pen to paper on his rookie contract with the Browns on Saturday, but because he missed all of training camp and preseason while he was unsigned following his July 12 arrest in Fort Lauderdale, Fla. on charges of domestic assault and battery, Cleveland was granted a two-game exemption in which the running back won't count toward the 53-man roster. Though all charges against Judkins have since been dropped, the NFL is still investigating the alleged incident, and the 21-year-old is scheduled to meet with league officials during the upcoming week. While it's still unclear if Judkins will be subject to any league discipline, the expectation is that he'll have the roster exemption lifted in advance of the Week 2 contest. Because of all the time he's missed this summer, Judkins could handle a light role initially for Cleveland, though Cameron Wolfe of NFL Network relays that the Browns are hopeful that Judkins will eventually emerge as the team's lead back. Dylan Sampson and Jerome Ford will take on the brunt of the snaps and touches out of the backfield for at least the Week 1 game, however.

McCaffrey (calf) remains listed as questionable for Sunday's game in Seattle, though he's still "trending" toward playing after he was a "big participant" in the 49ers' team walk-through Saturday, Ian Rapoport of NFL Network reports.

McCaffrey had enjoyed a healthy training camp and preseason before he unexpectedly popped up on the 49ers' injury report Thursday, when he was listed as a limited participant in practice due to a calf injury. Though McCaffrey's 2024 debut was delayed until Week 10 after he suffered a calf strain last August that was later reclassified as bilateral Achilles tendinitis, the 49ers appear to be more optimistic that the 29-year-old will avoid any missed games this time around. McCaffrey was listed as a non-participant in Friday's practice, but he was spotted doing some running off to the side and downplayed the calf injury when he spoke to reporters after the session. McCaffrey's inclusion in the walk-through Saturday represents another positive indicator that he'll suit up, but fantasy managers planning on using the star running back in Week 1 will still want to keep tabs on his status leading up to 4:05 p.m. ET kickoff. If the 49ers ultimately decide to hold McCaffrey out of the contest or limit his workload, Brian Robinson and Isaac Guerendo would be in line for enhanced roles out of the backfield.

Prentice was elevated from the practice squad to the Broncos' active roster Saturday, Aric DiiLalla of the team's official site reports.

Prentice was released and then added to the Broncos' practice squad at the end of August, but he was always tabbed to be the team's fullback. He'll likely draw part-time offensive snaps in Week 1 against the Titans.

Washington was elevated from Atlanta's practice squad Saturday, Terrin Waack of the team's official site reports.

Washington failed to make Atlanta's initial roster but re-signed with the practice squad. If he's active for Sunday's game against Tampa Bay, he'll be fourth on the running back depth chart.

The Lions signed Saylors off their practice squad Saturday.

With Sione Vaki (hamstring) out for Week 1 against the Packers, Saylors was signed to the 53-man roster as the Lions' RB4 behind Jahmyr Gibbs, David Montgomery and special teams dynamo Craig Reynolds. Saylors carried the ball 33 times during the preseason, totaling 112 scoreless yards.

The Colts elevated Bentley from the practice squad Saturday.

It's unclear if Bentley's activation is related to Tyler Goodson's (elbow) questionable status. If active for Sunday's game against the Dolphins, Bentley will provide backfield depth behind Jonathan Taylor and DJ Giddens. Bentley produced a 22-94-2 rushing line during the preseason.

Scott (ankle) has been ruled out for Monday night's game against the Bears.

Scott was injured in the Vikings' preseason finale back on Aug. 22 and will be unavailable for the team's Week 1 opener. He was unlikely to see much, if any, playing time to begin with behind Aaron Jones, Jordan Mason and Ty Chandler.

Smith returned two kickoffs for 63 yards during Kansas City's 27-21 loss to the Chargers on Friday night.

Smith impressed in the return game Week 1, but the rookie seventh-round pick wasn't called upon to handle any actual carries, and he played just eight percent of offensive snaps. Still, it's encouraging to Smith's prospects that Elijah Mitchell was a healthy scratch Friday. Smith figures to operate as the No. 3 running back behind Isiah Pacheco and Kareem Hunt again in Week 2 against the Eagles.

McCaffrey (calf), who is officially listed as questionable for Sunday's road game against the Seahawks, is expected to suit up unless he suffers any setbacks, Ian Rapoport of NFL Network reports.

McCaffrey surfaced on San Francisco's injury report with a calf issue Thursday and was officially listed as limited, but he was then downgraded to being a non-participant Friday. Still, McCaffrey was running on the side field Friday and told David Lombardi of SFStandard.com that he "feels great physically" and plans to play through the calf injury, which he described as "minor." While McCaffrey's status for Week 1 may not be made official until 90 minutes ahead of Sunday's 4:05 p.m. ET kickoff, it sounds like he'll take the field barring an unexpected development during pre-game warmups.