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Javonte Williams RB | DAL
Cowboys' Javonte Williams: Makes three trips to end zone in Week 4 win
Williams carried the ball 19 times for 62 yards and three touchdowns while catching all five of his targets for 21 yards in Sunday's 34-30 win over the Texans.
A 16-6 lead for Houston at the half transformed into a barn burner that saw Williams hit paydirt on three straight possessions to begin the second half, with his TD runs coming from eight, one and two yards out. The 26-year-old running back is proving his 2025 breakout was no fluke, and through four games to begin the current campaign he's scored six touchdowns (five on the ground, one through the air) while putting together 308 scrimmage yards. Williams will look to keep rolling in a Week 5 home tilt against the Buccaneers.
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Bhayshul Tuten RB | JAC
Jaguars' Bhayshul Tuten: Good production with 19 touches
Tuten rushed 17 times for 73 yards and brought in both targets for 18 yards in the Jaguars' 22-17 win over the Bengals on Sunday.
Tuten filled his usual role as the clear lead option in Jacksonville's ground attack with aplomb, grinding out tough yards on many of his carries and also contributing a 20-yard run. He also recorded multiple receptions for the third consecutive game, and although he saw backfield mate Chris Rodriguez score the Jaguars' only rushing touchdown of the day, that came on a breakaway run from 25 yards out as opposed to in close. Tuten has at least 15 carries in three of his first four games heading into a Week 5 showdown against the Eagles in London next Sunday.
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Bucky Irving RB | TB
Buccaneers' Bucky Irving: Modest production with 16 carries
Irving rushed 16 times for 61 yards in the Buccaneers' 17-14 loss to the Packers on Sunday.
Irving was surprisingly held without a single target in the narrow loss, despite rookie quarterback Jaydon Daniels being under center and the third-year running back being a highly trustworthy safety valve out of the backfield. Irving worked hard for his yards on the ground as well, with his longest run of the day going for only seven yards. Irving has yet to eclipse 89 rushing yards in any of his first four games, and with reports Baker Mayfield may be in line for close to a two-month absence due to his thumb injury, the former may have to get accustomed to running against loaded defensive fronts for the foreseeable future.
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Kyren Williams RB | LAR
Rams' Kyren Williams: Two late TDs in comeback win
Williams rushed 16 times for 80 yards and two touchdowns while catching 10 of 13 targets for 67 yards in Sunday's 24-20 win over the Eagles.
Williams led the team in targets and catches, finishing with one more of each than Puka Nacua, though Nacua racked up 125 receiving yards in his return from a hip injury. Nacua also scored the Rams' first touchdown on a two-yard run, but Williams proceeded to score twice in the final four minutes of the fourth quarter, with touchdown runs of one yard and seven yards to complete the Rams' comeback. Backup Blake Corum had just six touches, so Williams is locked in as the primary backfield option for the Rams ahead of a Week 5 home game against the Bills.
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Kyle Monangai RB | CHI
Bears' Kyle Monangai: Tending to thumb issue
Coach Ben Johnson said after Sunday's 23-12 win against the Jets that Monangai suffered a thumb injury during the contest, Kevin Fishbain of The Athletic reports.
Monangai ripped off 30 carries for 146 yards and two touchdowns to go with a four-yard catch on his only target in Week 4, while fellow RB D'Andre Swift notched 15 rushes himself for 58 yards and hauled in both of his targets for 16 yards. Perhaps the breakdown of RB touches among them is related to the knee injury that Swift tended to in advance of this game, but in any case Monangai now is dealing with a health concern of his own. The statuses of the two thus will bear monitoring as Chicago gears up for an NFC North road showdown with the Packers next Sunday.
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D'Andre Swift RB | CHI
Bears' D'Andre Swift: Outplayed by Monangai in Week 4
Swift rushed 15 times for 58 yards and caught both of his targets for 16 yards in Sunday's 23-12 win over the Jets. He also lost a fumble.
Swift was stopped twice inside the 1-yard line on the opening drive, with the second stop resulting in a turnover on downs. Kyle Monangai got the goal-line opportunities on Chicago's next possession and punched in a one-yard touchdown. Swift also lost a fumble in the third quarter and watched Monangai dominate touches the rest of the way, as the latter finished with 146 rushing yards and two touchdowns on 30 carries. Both of Chicago's top two running backs are likely to play significant roles in Week 5 against Green Bay's shoddy run defense, assuming Monangai is able to play through the thumb injury he sustained during Sunday's win.
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Tank Bigsby RB | PHI
Eagles' Tank Bigsby: Exits Sunday's game
Bigsbu (undisclosed) left Sunday's game in the fourth quarter and went to the sideline tent, Jimmy Kempski of PhillyVoice.com reports.
In a contest in which Saquon Barkley was lost early due to a hamstring injury, Bigsby was the primary beneficiary before his own exit late, accounting for 55 yards on 14 carries. Will Shipley is the only healthy running back currently on the Eagles' active roster.
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Reggie Gilliam RB | NE
Patriots' Reggie Gilliam: Returns vs. Buffalo
Gilliam (ankle) has returned to Sunday's game against the Bills, Mike Reiss of ESPN.com reports.
Gilliam had to be carted off the field after sustaining an ankle injury. However, the veteran fullback passed the medical staff's tests and was back on the field for the second half.
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Jacory Croskey-Merritt RB | WAS
Commanders' Jacory Croskey-Merritt: Held in check by Indy
Croskey-Merritt carried the ball nine times for a season-low 15 yards and caught two of four targets for 35 yards in Sunday's 30-13 loss to the Colts.
The Commanders' running game struggled to get anything going against an Indy front seven led by DeForest Buckner, especially once Marcus Mariota (knee) was replaced under center by seventh-round rookie Athan Kaliakmanis, but Croskey-Merritt was able to salvage his production to some extent with a 35-yard catch and run on a screen pass in the first quarter that helped set up a field goal. His 11 touches led the Washington backfield, while Austin Ekeler saw five in his season debut and rookie Kaytron Allen got three, but that division of labor came with Rachaad White (shoulder) on the shelf. Croskey-Merritt's ability to improve on his numbers could depend on whether Jayden Daniels (elbow) can return at quarterback for Washington in a Week 5 home game against the Giants.
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Jordan James RB | SF
49ers' Jordan James: Healthy scratch for Week 4
James (coach's decision) is inactive against Denver on Sunday.
The second-year pro will observe Sunday's game from the sidelines while the 49ers roll with two active running backs in Christian McCaffrey and rookie Kaelon Black. James' next chance to play is Week 5 against the Seahawks on Sunday, Oct. 11.