Pierce has one carry for two yards in Monday's 34-10 win over Dallas. He also returned one kickoff for five yards.

Pierce was given just four snaps on offense, as the Texans made it the Joe Mixon show in primetime. Mixon typically dominates the backfield, but his 81 percent share of the snaps was a season high. This was Pierce's first game back after missing the previous two due to a groin injury, so his workload could tick up as he puts the issue further behind him.

Dowdle rushed 10 times for 28 yards while catching two of five targets for six yards in Monday's 34-10 win over Houston.

Dowdle got his head coach's vote of confidence prior to Monday's kickoff, and Mike McCarthy's words rang true after the tailback led Dallas in carries. That's where the good news ended, as the 26-year-old struggled to generate any room to operate in a blowout loss. Unlike star teammate CeeDee Lamb, Dowdle's value may have taken a significant hit by Dak Prescott's (hamstring) season-ending injury. With little threat of a passing attack, opposing defenses can stack the box against Dowdle and Co. like the Texans successfully accomplished Monday. Dowdle should still carry deep-league value, but those in standard formats may have to make difficult decisions as the fantasy playoffs inch closer.

Mixon rushed 20 times for 109 yards and three touchdowns and secured two of four targets for 44 yards in the Texans' 34-10 win over the Cowboys on Monday night.

A week after being bottled up by a talented Lions defense, Mixon was right back to dominating the opposition with a stellar effort on the ground. Mixon struck early, rattling off a 45-yard touchdown run to cap off the opening drive of the game and subsequently recording a one-yard scoring rush late in the first quarter. The prolific back would replicate the latter feat with 3:16 remaining to close out the scoring on the night, recording a new single-game-high TD total in the process. Mixon also curiously posted his second straight two-catch, 44-yard showing, affording him plenty of momentum ahead of a Week 12 home date with the division rival Titans.

Charbonnet rushed four times for three yards and caught two passes (two targets) for two yards in Sunday's 20-17 win over the 49ers.

Charbonnet continues to serve as the distant No. 2 running back behind Kenneth Walker, who produced 59 yards and a touchdown on 16 touches. Even worse, Charbonnet was quite inefficient in Sunday's win. While he's worth holding onto in case Walker gets injured, Charbonnet has minimal standalone value.

Luepke (calf) is inactive for Monday's Week 11 game against Houston, Nick Harris of the Fort Worth Star-Telegram reports.

This was expected, as Luepke didn't practice at all this week and was deemed doubtful after the Cowboys' final practice. While the second-year fullback hasn't gotten more than four touches in any of his nine games so far this season, he's a key part of the team's running game as a blocker. Those duties could fall upon backup tight ends Luke Schoonmaker and/or Brevyn Spann-Ford with Luepke unable to suit up against the Texans.

Johnson carried twice for three yards during Sunday's 52-6 loss to the Lions.

The 28-year-old suited up after being considered questionable with a hamstring injury, and he played just 27 percent of the offensive snaps. Johnson has five carries for 12 yards and one reception for 20 yards over the past four games, and he isn't likely to be significantly involved in the offense while Travis Etienne is healthy.

The Packers reinstated Lloyd (ankle/hamstring/appendix) from injured reserve Monday.

Though Lloyd will temporarily get added back on the 53-man roster, Matt Schneidman of The Athletic relays that the rookie running back will likely be returned to IR or another reserve list after he required an emergency appendectomy Friday. Lloyd had missed the Packers' final seven games before a Week 10 bye due to a high-ankle sprain, but he had his 21-day evaluation window opened last Monday. However, Lloyd was a limited participant in just two practices on account of the ankle sprain as well as a hamstring injury before he reported abdominal pain and was diagnosed with appendicitis. Assuming he's eventually placed back on a reserve list, Lloyd would have to miss at least another four games, but he would still be eligible for activation again beginning Week 16.

Chandler didn't have a carry or reception in Sunday's win at Tennessee. He did have one kick return for 35 yards.

Chandler played just one snap on offense as he's become a distant third option at running back behind starter Aaron Jones and backup Cam Akers.

Goodson did not have a carry or reception in Sunday's win at the Jets.

Goodson played just two snaps on offense as Jonathan Taylor played on 63 of the offense's 70 snaps. Trey Sermon (five snaps) did play more snaps than Goodson, but it may be Goodson that has more of a role as a pass catcher if the Colts fall far behind. Either way, neither Sermon nor Goodson currently has much of a role if Taylor is fully healthy.

Sermon had one reception for three yards on his only target and did not have a carry in Sunday's win at the Jets.

He played just five snaps on offense as Jonathan Taylor played on 63 of the offense's 70 snaps. Sermon did play more snaps than Tyler Goodson (two snaps), but it may be Goodson that has more of a role as a pass catcher if the Colts fall far behind. Either way, neither Sermon nor Goodson currently has much of a role if Taylor is fully healthy.