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Joe Flacco QB | CIN
Browns' Joe Flacco: Pair of picks in Week 4 loss
Flacco completed 16 of 34 passes for 184 yards with no touchdowns and two interceptions while adding three rushes for minus-1 yard in the Browns' 34-10 loss to the Lions on Sunday. He also lost a fumble.
Flacco's ragged stat line tells the tale of a tough afternoon against an aggressive Lions defense that sacked him three times in addition to the three turnovers. The veteran signal-caller did keep Cleveland competitive for a significant part of the contest before Detroit pulled away with 14 fourth-quarter points, but with a 2:6 TD:INT and 58.1 percent completion rate through four games, it may not be long before Flacco is swapped out for one of Cleveland's rookie QBs, Dillon Gabriel or Shedeur Sanders. However, Daniel Oyefusi of ESPN.com reports a switch may not yet be in the works just yet, as head coach Kevin Stefanski confirmed after the game he's still not considering a quarterback change.
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Rome Odunze WR | CHI
Bears' Rome Odunze: Scoring binge continues Sunday
Odunze had four receptions on eight targets for 69 yards and a touchdown in Sunday's 25-24 win over the Raiders.
Odunze's scoring onslaught continued when he gutted the Raiders' secondary for a 27-yard touchdown on Chicago's first possession of the second half. The breakout fantasy star has generated five touchdowns during his impressive four-game scoring streak to kick off the season. Odunze's eight targets Sunday were on par with his 8.8 average through four weeks, giving fantasy managers a reliable WR1 asset so far. The talented sophomore will attempt to extend his scoring streak when the Bears resume play against the Commanders in Week 6 on Oct. 13 following the team's upcoming bye.
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Patrick Mahomes QB | KC
Chiefs' Patrick Mahomes: Four touchdowns against Baltimore
Mahomes completed 25 of 37 passes for 270 yards, four touchdowns and no interceptions in Sunday's 37-20 win over Baltimore. He added four rushes for five yards.
Mahomes turned in a vintage effort, perhaps not coincidentally as the return of Xavier Worthy reinforced his wide receiver corps. Mahomes threw four touchdowns in a regular-season game for the first time since Week 10 of the 2023 season, with all four scores coming in the red zone. He primarily attempted passes in the short areas of the field but still recorded six completions of at least 15 yards. This was Mahomes' first game with multiple touchdowns this season, and it also accounted for his highest yardage total of 2025. If Worthy's shoulder holds up, Mahomes could be in for much improved results as the campaign progresses -- particularly once Rashee Rice (suspension) is eligible to return in Week 7.
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Bryce Young QB | CAR
Panthers' Bryce Young: Serviceable numbers in loss
Young completed 18 of 30 passes for 150 yards with one touchdown and no interceptions while adding one rush for three yards in the Panthers' 42-13 loss to the Patriots on Sunday.
Young was pulled late for Andy Dalton in the 29-point defeat, and the third-year signal-caller was largely ineffective most of the afternoon. The highlight of his performance came very early, as Young capped off a crisp seven-play opening possession with a seven-yard touchdown pass to Tommy Tremble. The now 1-3 Panthers will try to capitalize on what should be a favorable matchup against the middling Dolphins defense in a Week 5 home clash next Sunday, but coach Dave Canales' patience with Young may be wearing a bit thin.
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A.J. Brown WR | NE
Eagles' A.J. Brown: Forgettable numbers in loss
Brown brought in two of nine targets for seven yards in the Eagles' 31-25 win over the Buccaneers on Sunday.
After coming to life with a 6-109-1 line against the Rams in Week 3, Brown's production slumped again. The veteran wideout's yardage total was a new season low and his second single-digit yardage figure over the first four games of 2025. Jalen Hurts did try to get the ball in Brown's hands however, and he has 27 targets in his last three contests. Brown could struggle once again to build momentum as the Broncos' suffocating secondary comes to town next Sunday afternoon for a tough Week 5 matchup.
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Blake Grupe K | LAR
Saints' Blake Grupe: Hits long field goal in loss
Grupe went two of two on field-goal attempts, including a 54-yarder, and made his only extra-point try in Sunday's 31-19 loss to the Bills.
The kicker also nailed a 35-yarder in the fourth. Grupe has yet to miss an extra point in 2025, though he has missed three field goals. Perhaps Sunday's performance can get him and the 0-4 Saints on track with the Giants looming next week.
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Ka'imi Fairbairn K | HOU
Texans' Ka'imi Fairbairn: Makes two FGAs in Week 4
Fairbairn went 2-for-3 on field-goal tries and made both of his extra-point attempts in Sunday's 26-0 win over the Titans.
Fairbairn made a 47-yard field goal in the first quarter and a 43-yarder in the second quarter before later missing a 54-yard attempt wide right in the third quarter. The kicker has now gone 8-for-10 on field-goal attempts, including 3-for-5 from 50-plus yards, over four games this season.
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Derrick Henry RB | BAL
Ravens' Derrick Henry: Quiet against Kansas City
Henry carried the ball eight times for 42 yards in Sunday's 37-20 loss to Kansas City. He added two receptions on three targets for 16 yards.
The Ravens attempted only 17 rushes as a team, with Lamar Jackson accounting for six of those before he exited with a hamstring injury. That left Henry with limited volume, with four rushes in each half. He performed efficiently enough by gaining double-digit yards on two carries and one reception, but the game script ultimately held him back. Henry has had a poor start to the season with three lost fumbles in high-profile situations, and he's now been held to 50 or fewer rushing yards in three consecutive games for the first time since 2018.
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Stefon Diggs WR | WAS
Patriots' Stefon Diggs: Over 100-yard mark in win
Diggs brought in six of seven targets for 101 yards in the Patriots' 42-13 win over the Panthers on Sunday.
Drake Maye threw for a relatively modest 203 yards on the afternoon in the easy victory, but Diggs accounted for about half of that in his best game yet as a Patriot. The veteran wideout led New England's pass catchers across the board, including a team-best 33-yard reception, and the performance could serve as a launchpad for Diggs ahead of a marquee Week 5 divisional showdown against his old Bills teammates next Sunday night.
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Tyler Loop K | BAL
Ravens' Tyler Loop: Good day despite loss
Loop hit both of his field-goal tries and both of his extra-point attempts in Sunday's 37-20 loss to the Chiefs.
The rookie kicker drilled a 43-yard field goal in the second quarter and a 32-yarder in the third. Loop has now made all seven field-goal attempts and 14 of 15 extra-point tries in 2025. Five of his field goals have come from 40 yards or longer, too.