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Anthony Bradford G | SEA
Seahawks' Anthony Bradford: Questionable for Sunday's game
Bradford (knee) is listed as questionable for Sunday's game against the Cardinals, John Boyle of the Seahawks' official site reports.
Bradford was limited in the Seahawks' first two practices of the week before sitting out Friday's session altogether. If Bradford is indeed inactive on game day, Christian Haynes is set to start at right guard.
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Isaac Seumalo G | ARI
Cardinals' Isaac Seumalo: Questionable for Week 2
Seumalo (shoulder) is listed as questionable for Sunday's game against the Seahawks, Tyler Drake of ArizonaSports.com reports.
Seumalo drew the questionable tag after logging back-to-back limited practices to end Week 2 prep. Hayden Conner would likely start at left guard if Seumalo is unable to play. The Cardinals could be without both of their starting guards in Seumalo and Isaiah Adams (knee) against the defending Super Bowl champions.
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Cole Van Lanen G | JAC
Jaguars' Cole Van Lanen: Will suit up at Denver
Van Lanen (knee) does not carry an injury designation ahead of Sunday's game against the Broncos, Ryan O'Halloran of The Florida Times-Union reports.
Van Lanen was limited at practice Wednesday and Thursday with a nagging knee issue, but he managed a full session Friday, so it looks like he'll be available in Week 2. He should make another start at right tackle Sunday.
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Isaiah Adams G | ARI
Cardinals' Isaiah Adams: Iffy for Week 2 vs. Seattle
Adams (knee) is listed as questionable for Sunday's game against the Seahawks, Tyler Drake of ArizonaSports.com reports.
Adams was a limited participant in all three practices this past week due to a knee injury that prevented him from suiting up for the Cardinals' Week 1 win over the Chargers. If he's unable to play against Seattle, then Jon Gaines would likely start at right guard for a second consecutive game.
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Francis Mauigoa OT | NYG
Giants' Francis Mauigoa: Nursing shoulder injury
Mauigoa was a limited participant in Friday's practice due to a shoulder injury, Dan Salomone of the Giants' official site reports.
Mauigoa may have picked up the injury during the Giants' Week 1 win over the Cowboys, and his shoulder issue has limited his practice participation in each of the last two days. Saturday's practice is his last opportunity to upgrade his participation and avoid an injury designation for Monday's game against the Rams.
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Dametrious Crownover OT | NE
Patriots' Dametrious Crownover: Ruled out for Sunday
Crownover (knee) has been ruled out ahead of Sunday's game against the Steelers.
Crownover missed all three practice sessions during Week 2 prep with a new knee injury. The rookie sixth-rounder will leave the Patriots thin on the offensive line as they head into a matchup with a Steelers defense that held the Falcons to 13 points in Week 1.
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Josh Simmons OT | KC
Chiefs' Josh Simmons: Won't play vs. Colts
Simmons (back) is officially listed as out for Sunday's game versus Indianapolis, Matt McMullen of the Chiefs' official site reports.
Simmons was unable to practice during the week as he continues to deal with a back injury, and he'll have to wait at least one more game to make his 2026 regular-season debut. Undrafted rookie Kahlil Benson projects to get another start at left tackle in Week 2.
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Andrew Thomas OT | NYG
Giants' Andrew Thomas: Working through ankle injury
Thomas was a limited participant in Friday's practice due to an ankle injury, Dan Salomone of the Giants' official site reports.
Thomas has opened the week with back-to-back limited practices due to an ankle injury that he may have picked up during the Giants' Week 1 win over the Cowboys. A full practice Saturday would likely be enough for the seventh-year pro to avoid an injury designation for Monday's game against the Rams.
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Miles Killebrew SAF | TB
Buccaneers' Miles Killebrew: Questionable for Week 2
Killebrew (concussion) is listed as questionable for Sunday's game against the Browns.
Killebrew was able to practice in full Friday, but he still drew the questionable tag while working through the league's five-step concussion protocol. The last step is to pass an evaluation by an independent neurologist, at which point Killebrew would be cleared to play against Cleveland.