Lewis recorded 43 total tackles (33 solo), four passes defensed and two forced fumbles across 17 regular-season games in 2025.
After starting six games and playing 569 defensive snaps during the Bills' 2024 campaign, Lewis started just four contests and logged 370 defensive snaps this regular season. Despite this, the Buffalo product remained a key contributor, tying for the fourth-most passes defensed while playing 222 special-teams snaps. Set to hit unrestricted free agency this offseason, Lewis will likely draw interest from teams in need of secondary depth ahead of the 2026 season.
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Bills' Cam Lewis: Returns vs. Denver
Rotowire
Lewis (undisclosed has returned to Buffalo's divisional-round matchup versus the Broncos on Saturday, Katherine Fitzgerald of The Buffalo News reports.
Lewis is back in action after briefly exiting the game at the end of the first half due to cramping. Darnell Savage filled in at safety while Lewis was sidelined.
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Bills' Cam Lewis: Questionable to return
Rotowire
Lewis (cramps) is questionable to return Buffalo's divisional-round matchup versus the Broncos on Saturday.
Lewis is currently dealing with cramping, which caused him to exit the game late in the first half. Darnell Savage will replace Lewis at safety if he ends up being unable to return.
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Bills' Cam Lewis: Questionable for Week 16
Rotowire
Lewis (hamstring) is listed as questionable ahead of Sunday's matchup against the Browns.
Lewis popped up on the Bills' injury report due to a hamstring injury Thursday, logging two consecutive limited sessions to end the week of practice. The 28-year-old has appeared in all 14 of Buffalo's games this season, recording 35 total tackles, four passes defensed and two forced fumbles. If active for the Week 16 contest, Lewis will likely play a reserve role in the Bills' secondary.
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Bills' Cam Lewis: Questionable for Sunday
Rotowire
Lewis (calf) is listed as questionable ahead of Sunday's matchup against the Buccaneers.
Lewis was a limited participant in all three practices this week with a calf injury. The slot cornerback was able to play through a shoulder injury in the Bills' Week 10 loss to the Dolphins despite logging limited sessions throughout that week as well. The 28-year-old's status for Sunday's game may also revolve around starting slot cornerback Taron Johnson (groin) and his availability. If Lewis is able to suit up, he will likely either back up a starting Johnson or share slot cornerback snaps with fellow University at Buffalo product Ja'Marcus Ingram if Johnson is unable to go for a third straight week.
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Bills' Cam Lewis: Questionable for TNF
Rotowire
Lewis (shoulder) is questionable to play in Thursday night's contest in Miami.
Lewis was a limited participant at practice throughout the week while dealing with an apparent shoulder injury. The 28-year-old operates as a depth option at both safety and cornerback with Buffalo, so his absence would carry some significance for the team. If he can't go in Week 3, Brandon Codrington and Sam Franklin would be candidates to see an increase in workload.
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Bills' Cam Lewis: Logs full practice Wednesday
Rotowire
Lewis (calf) was not listed on Buffalo's injury report Wednesday.
Lewis dealt with a calf injury during training camp that forced him to miss some preseason action, but it appears he'll be healthy for Sunday's game versus the Ravens. He figures to play a depth role in the Bills' defensive backfield in 2025.
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Bills' Cam Lewis: Not playing Sunday
Rotowire
Lewis (calf) isn't suiting up for Sunday's preseason game against the Bears, Lance Lysowski of The Buffalo News reports.
Lewis appears to have picked up an apparent calf injury during training camp and he will now be forced to miss Buffalo's second preseason contest. The safety will look to return to the field for Saturday's preseason finale in Tampa Bay.
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Bills' Cam Lewis: Has career-best season
Rotowire
Lewis recorded 68 tackles (47 solo) and four passes defensed, including an interception, over 17 regular-season games in 2024.
After not reaching 150 defensive snaps in any of his first four seasons as a pro, Lewis was on the field for 569 defensive snaps in 2024. This was due in large part to injuries to other Buffalo defensive backs, most notably a four-game absence from regular starting slot cornerback Taron Johnson early in the season. Lewis is slated to return to the Bills in 2025, and the team may need to shake up its corner rotation if Rasul Douglas leaves in free agency.
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Bills' Cam Lewis: Inks new deal
Rotowire
Lewis re-signed with the Bills on a two-year contract Monday.
Lewis will remain in Buffalo after a 2023 campaign that saw him play a career-high 134 snaps on defense and 319 special-teams snaps in 17 regular-season contests. The 26-year-old will likely maintain a limited role on defense in 2024, but he'll work to carve out a larger role there during the team's offseason programs.
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Bills' Cam Lewis: Active Sunday
Rotowire
Lewis (shoulder) is active for Sunday's game against the Patriots, Alaina Getzenberg of ESPN.com reports.
The cornerback carried a questionable tag into Sunday. Lewis was active last Sunday versus the Giants but did not see any defensive snaps. The fifth-year depth player has six tackles in six games this season.
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Bills' Cam Lewis: Questionable for divisional matchup
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Lewis is listed as questionable for Sunday's game at New England due to a shoulder issue, Alec White of the Bills' official site reports.
Lewis is normally a depth piece on defense, not exceeding 14 percent of the defensive snaps in any game this season, but the Bills have been working with a thin secondary ever since Tre'Davious White was lost for the season with a torn Achilles, so every healthy body matters.
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Bills' Cam Lewis: Returns in full Friday
Rotowire
Lewis (forearm/illness) was listed as a full participant on Friday's practice estimate and doesn't carry an injury designation heading into Sunday's game against the Browns.
Lewis missed both Wednesday's and Thursday's practice sessions as the result of an illness and forearm issue, but he's since been marked down as a full participant on Friday's practice estimate and expects to be made available for the Week 11 matchup versus Cleveland. With Jordan Poyer (elbow) currently at risk of missing his third consecutive game, Lewis might be looking at another busy afternoon as one of the Bills' starting safeties alongside Damar Hamlin.
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Bills' Cam Lewis: Misses Wednesday's session
Rotowire
Lewis missed practice Wednesday due to a forearm injury/illness.
Of course, Bills fans were feeling ill after Lewis failed to bat the ball down on a 4th-and-18 play that would have sealed Sunday's game against the Vikings, but to his credit he owned up to the error. We're not sure if either issue is serious for Lewis or if he just needs more of a maintenance day. Lewis was thrown into heavy action in Week 10 due to the Buffalo secondary being so banged up, and he posted a career-high nine tackles.
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Bills' Cam Lewis: Not listed on injury report
Rotowire
Lewis (nose) isn't listed on the Bills' injury report Monday.
Lewis suffered a nose injury during Friday's preseason finale but appears healthy heading into Thursday's season-opening matchup against the Rams. The third-year defensive back has appeared in 12 games over the last two seasons with Buffalo, posting 14 tackles and one forced fumble.
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Bills' Cam Lewis: Heads to COVID list
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Lewis was placed on the reserve/COVID-19 list Monday, Chris Brown of the Bills' official site reports.
The cornerback tested positive for the virus, according to Tom Pelissero of NFL Network. Even though the Bills pulled off a major win Sunday at New England, like a lot of teams, they are starting to suffer multiple hits due to injuries and COVID-19-related issues. Lewis has seen more than 50 percent of the special-teams snaps the last two weeks. If he's vaccinated, he'll have time to clear the protocols and not miss any action heading into Sunday's game against the Falcons.
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Bills' Cam Lewis: Injured in loss
Rotowire
Lewis suffered a wrist injury early in Monday's loss to the Chiefs and did not return, Chris Brown of the Bills' official site reports.
That explains Lewis' low snap count of 10 defensive plays in a game where he received a surprise start as the third cornerback over Taron Johnson. Lewis did not record any stats in his abbreviated outing. We'll see if he can shake the injury quickly in what's now a short week before the Week 7 contest at the Jets.
