Alvarez is out of the lineup for Thursday's contest against the Rockies, Matt Kawahara of the Houston Chronicle reports.

Alvarez started in both of the past two days upon his return from the 60-day injured list, but he will get a breather for Thursday's matinee. Jose Altuve will occupy the designated-hitter spot and Mauricio Dubon will cover left field in the rubber match.

McCutchen is absent from the lineup for Thursday's tilt in St. Louis.

McCutchen will get a routine day off after starting in the previous two games and five of the last six contests. Bryan Reynolds will serve as the Pirates' designated hitter Thursday, while Jack Suwinski will man right field.

Smith (quadriceps) is out of the lineup for Thursday's game against the Brewers.

After exiting early in Wednesday's 3-2 win due to left quad tightness, Smith will take a seat for Thursday's matinee contest. The Diamondbacks seem to be classifying Smith as day-to-day, and even if he had emerged from Wednesday's contest without an injury, he likely would have been in line to sit Thursday since the Brewers are sending a lefty starter (Jose Quintana) to the bump. Tyler Locklear will get the nod at first base in the series finale.

Manzardo started at DH and went 1-for-5 with an RBI in Wednesday's 4-3 extra-inning win over the Rays.

Manzardo delivered a run-scoring single in the bottom of the 10th inning, as Cleveland walked off Tampa Bay for its second consecutive win. Manzardo's had a hand in each, knocking in the game-winning run in both victories. With the Guardians moving on from Carlos Santana, who was placed on outright waivers Tuesday, Manzardo is poised for regular playing time through the end of the season.

Devers went 4-for-4 with a pair of home runs, a double, a walk, four total runs and five total RBI in a 12-3 victory versus the Cubs on Wednesay.

Devers ignited San Francisco's offense early with a first-inning solo blast. He added a run-scoring double in the third and a three-run homer in the sixth. Devers finished with his fourth four-hit game of the campaign, and his five RBI trailed only his May 23 eight-RBI performance against the Orioles for his most this season. In fact, Devers tallied more RBI on Wednesday than he had in his previous 15 games combined.

Ohtani (1-1) earned the win over Cincinnati on Wednesday, allowing one run on two hits and two walks while striking out nine batters over five innings.

Ohtani gave up a solo homer to Noelvi Marte in the third inning, but the Reds otherwise weren't able to do much against him. The two-way star got 14 whiffs on his 87 pitches and fanned a season-high nine batters. Of note, Ohtani threw 23 curveballs Wednesday -- per Jack Harris of the Los Angeles Times, which blew away his previous career-high total of 16. It's equally important that Ohtani was allowed to finish the fifth inning -- it was the first time this season he's gone that deep, which by rule means it's the first time he was able to qualify for a victory. That's a significant development for fantasy managers, as the Japanese superstar should be able to help in that category moving forward while potentially building upon his already impressive 44:7 K:BB through 32.1 frames.

Pederson went 2-for-6 with a three-run home run, two additional RBI and two additional runs scored during Wednesday's 20-3 win over the Angels.

Pederson lifted his fifth home run of August with a three-run blast off Jack Kochanowicz in the second inning and extended his hit streak to seven games. The 33-year-old slugger set season highs in runs scored and RBI during the offensive outburst. His previous best RBI total was two. During his hit streak, Pederson has gone 9-for-28 (.321) with nine RBI and five runs scored.

Alvarez went 1-for-2 with a two-run home run and an additional run scored during Wednesday's 4-0 win over Colorado.

Alvarez was activated from the injured list ahead of Tuesday's series opener and went hitless with two walks in four plate appearances in his return. He walked twice more Wednesday and delivered his first hit since coming back by launching a two-run home run off Angel Chivilli in the fourth inning. Alvarez slashed .210/.306/.340 with three home runs across 121 plate appearances before being placed on the injured list back in May.

Smith was removed from Wednesday's game against the Brewers due to left quadriceps tightness.

Smith tweaked his quad while running out of the batter's box after hitting a single in the seventh inning, and he was immediately lifted for a pinch runner. The severity of his injury remains unclear, but more details may emerge after the game. If the 29-year-old ends up needing to miss time, Tyler Locklear would be the next man up to start at first base.

Rice went 3-for-5 with a solo home run and a second run scored in Wednesday's 11-2 win over the Nationals.

The Yankees launched six homers in total on the afternoon, with Rice's coming off Shinnosuke Ogasawara as part of a nine-run third inning -- only his sixth long ball of the season off a left-hander, compared to 16 off righties. Rice has bashed his way into a strong-side platoon role for New York as he splits his time between first base and catcher, and over his last 10 games he's batting .353 (12-for-34) with a double, a triple, five homers, eight runs and 11 RBI.