Mena (shoulder) has continued his throwing program, but he has yet to throw off a mound, Alex Weiner of ArizonaSports.com reports.

Mena has been out since early June after suffering a right shoulder strain, and he doesn't appear to be particularly close to returning to action. With less than a month left in the 2025 campaign, the right-hander may be running short on time. Mena will likely have to participate in multiple bullpen sessions and an eventual minor-league rehab assignment before he'd be able to return.

Hoffmann hasn't pitched since being optioned to Triple-A Reno on Aug. 20 while dealing with fatigue, Alex Weiner of ArizonaSports.com reports.

Reno hasn't yet placed Hoffmann on its injured list, so he could be back in action within a few days. Hoffmann has posted a 6.55 ERA and 2.00 WHIP over 11 innings in 10 appearances at the MLB level with the Royals and Diamondbacks this season.

DeSclafani (thumb) is expected to face live hitters Tuesday, Alex Weiner of ArizonaSports.com reports.

DeSclafani has been sidelined since Aug. 13 while dealing with right thumb inflammation, but he will now take a significant step in his recovery. If Tuesday's session goes well, the Diamondbacks will likely start to put together the framework for a minor-league rehab assignment for DeSclafani in the coming weeks.

Miller exited Wednesday's game against the Phillies in the top of eighth inning with an apparent injury, Jack Stern of BrewerFanatic.com reports.

Miller threw eight pitches in the top of the eighth inning, allowing one run on two hits, before the Brewers' trainer came out to the mound to examine the right-hander. Miller was removed from the game and replaced Rob Zastryzny. Milwaukee has an off day Tuesday before resuming its series with Philadelphia on Wednesday.

O'Brien (shoulder) was cleared to play catch Monday and could avoid the 15-day injured list, Daniel Guerrero of the St. Louis Post-Dispatch reports.

O'Brien underwent an MRI on Monday due to lingering right shoulder discomfort, but the Cardinals were encouraged by the imaging results and the reliever was allowed to resume throwing. While a stint on the IL has not been ruled out, O'Brien will be given a couple days to continue to recover to see if a long-term absence can be avoided. The 30-year-old has emerged as a late-inning bullpen arm for St. Louis this season, collecting a 1.69 ERA and 35:17 K:BB over 37.1 innings while notching two saves.

The Diamondbacks activated Thompson (shoulder) from the 15-day injured list Monday.

Thompson has been shelved since early July with a right scapular strain but is ready to go after making a pair of scoreless rehab appearances with Triple-A Reno. The 33-year-old could be in the mix for saves as part of an unsettled Diamondbacks bullpen.

The Padres recalled Reynolds from Triple-A El Paso on Monday.

Reynolds has appeared in 18 games for San Diego this season and owns a 5.55 ERA, 1.32 WHIP and 22:13 K:BB across 24.1 innings. He'll likely handle a low-leverage relief role during his upcoming stint with the Padres.

The Dodgers activated Kopech (knee) from the 60-day injured list Monday.

Kopech had surgery July 1 to repair a torn meniscus in his right knee, but he's ready to join the big-league bullpen after making seven rehab appearances with Triple-A Oklahoma City. The righty held an 11.81 ERA and 5:9 K:BB over 5.1 innings in those outings, so the Dodgers are likely to ease Kopech into high-leverage spots.

Brewers manager Pat Murphy said that Megill (elbow) has been playing catch and has a bullpen session scheduled for Thursday, Adam McCalvy of MLB.com reports.

Megill landed on the 15-day injured list last Wednesday with a Grade 1 right flexor strain, but he's aiming for a minimum-length stay on the IL and appears to be tracking toward achieving that goal. The reliever will be eligible for activation Sept. 9. Abner Uribe has been filling in as the Brewers' closer since Megill was placed on the shelf.

The Giants transferred Rodriguez (elbow) from the 15-day injured list to the 60-day IL on Monday.

Rodriguez needs Tommy John surgery and is expected to remain out through the end of the 2026 season. The All-Star reliever was electric out of the San Francisco bullpen this season, posting a 1.78 ERA, 0.89 WHIP and 67:11 K:BB across 50.2 innings. Rodriguez took over as the Giants' closer following the trade of Camilo Doval to the Yankees in late July, but Ryan Walker looks poised to see most of the save chances for San Francisco in September.