The Angels transferred Mederos (shoulder) from the 15-day injured list to the 60-day IL on Wednesday.

Mederos landed on the 15-day IL on Aug. 24 after he experiencing shoulder inflammation coming out of his third start of the season for the Angels, and his move to the 60-day IL now spells an end to his 2025 campaign. Assuming Mederos doesn't require any sort of procedure to address his shoulder injury, he should be back to full health for spring training, when he'll be looking to compete for a spot in the Halos' Opening Day rotation.

The Nationals claimed Lao off waivers from the Mariners on Wednesday and optioned him to Triple-A Rochester.

Lao has been knocked around during his brief time in the majors, but he's collected a 3.13 ERA and 73:19 K:BB over 69 innings this season at Triple-A Tacoma. He'll report to Rochester for now but could get a look with the major-league club before the end of the season.

Sewald (shoulder) threw live batting practice Monday at the Tigers' facility in Florida, MLB.com reports.

Sewald will likely face hitters on one or two more occasions before the Tigers send him out on a minor-league rehab assignment. Acquired from the Guardians on July 31, Sewald has yet to make his Tigers debut while recovering from a moderate teres major strain that he sustained prior to the trade. He's eligible to return from the 60-day injured list Sept. 10 and could be activated shortly after that date.

Thielbar tossed a scoreless inning of relief with a strikeout to record a hold in Tuesday's 4-3 win over Atlanta.

Thielbar is now up to 19 holds for the year, which is good for second on the team behind Brad Keller's 22. The veteran lefty has been locked in lately, as he's recorded nine straight scoreless appearances. Overall, Thielbar has an elite 1.99 ERA and 0.83 WHIP to go along with 48 strikeouts in 49.2 innings out of the bullpen this season, his first with the Cubs.

The Reds recalled Richardson from Triple-A Louisville on Wednesday.

Richardson will provide the Reds with a fresh arm after they went with a bullpen game in Tuesday's 12-9 loss to the Blue Jays. He's collected a 3.93 ERA and 30:20 K:BB over 36.2 frames during his time with the big club this season.

The Reds optioned Sanmartin to Triple-A Louisville on Wednesday.

Sanmartin gave the Reds 1.2 innings out of the bullpen in his lone day with the team, giving up one unearned run in Tuesday's loss to the Blue Jays. Lyon Richardson was recalled from Triple-A to take Sanmartin's spot on the active roster and in the bullpen.

Santana gave up one run on one hit and one walk in the ninth inning Tuesday to record his 12th save of the season in a 9-7 win over the Dodgers.

The right-hander had plenty of cushion, allowing him to convert his sixth straight save chance. Since a shaky five-run outing at Coors Field in his first appearance following David Bednar's trade to the Yankees, Santana has looked the part of the Pirates' closer, posting a 2.92 ERA, 0.97 WHIP and 8:4 K:BB over his last 12.1 innings.

The Mets recalled Herget from Triple-A Syracuse on Tuesday.

Herget was touched up for three runs over 2.1 innings in Tuesday's win over the Tigers. The righty reliever will operate in a low-leverage role in the Mets' bullpen down the stretch.

Chandler (2-0) picked up the win Tuesday over the Dodgers, giving up three runs on six hits over four relief innings in a 9-7 victory. He struck out three without walking a batter.

Entering the game in the third inning to piggyback Carmen Mlodzinski once again, Chandler racked up an impressive 22 called or swinging strikes on only 50 pitches (34 total strikes), but he also served up his first two homers in the majors, getting taken deep by Shohei Ohtani and Andy Pages. Through his first three appearances with the Pirates, Chandler has lasted exactly four innings each time, producing a 2.25 ERA, 0.83 WHIP and 9:1 K:BB. If the Bucs maintain that piggyback arrangement, the duo will be lined up to take the mound again this weekend at home against the Brewers -- setting up a potential marquee matchup of flame-throwing rookies between Chandler and Jacob Misiorowski.

The Mariners signed Zuniga to a minor-league contract Tuesday.

Zuniga had spent the entirety of the season at Triple-A Lehigh Valley in the Phillies organization before being released last week. The 26-year-old posted a 5.14 ERA and 43:20 K:BB over 42 innings with Lehigh Valley and will give the Mariners some relief depth at Triple-A Tacoma.