Lawrence completed 21 of 31 pass attempts for 174 yards and a touchdown while taking seven carries for seven yards in Sunday's 26-21 win over the 49ers.

Lawrence played the role of game manager Sunday, protecting the football with safe, short throws en route to Jacksonville's third win of the season. It was still a lackluster showing from a fantasy perspective after the fifth-year pro failed to score multiple touchdowns for the third time in four starts this year. Lawrence has the Jaguars atop the AFC South, but his play does not inspire much optimism in fantasy circles heading into a tough matchup against Kansas City next Monday.

Smith completed 14 of 21 pass attempts for 117 yards, two touchdowns and three interceptions while adding 31 rushing yards on four attempts in Sunday's 25-24 loss to the Bears.

Smith threw an interception in each of the first three quarters before the Bears mounted a comeback in the fourth. The veteran signal-caller was coming off a mistake-free, three-touchdown performance in Week 3, but a pair of three-interception outings have sandwiched that strong showing. Smith will be a risky play against a tough Indianapolis defense next Sunday.

Jones completed 24 of 33 passes for 262 yards, one touchdown and two interceptions in Sunday's 27-20 loss to the Rams.

Jones continued to operate the Colts' offense efficiently, averaging 7.9 yards per attempt with three completions of more than 20 yards. He also appeared to have found Adonai Mitchell for a second touchdown on a 76-yard connection, but the wideout fumbled the ball through the end zone for a touchback. Jones made some mistakes of his own, throwing two interceptions on underthrown deep passes -- the latter of which came late as the Colts were trying to tie the game. Jones has passed for at least 250 yards in three of four games this season, though he has only one score in consecutive contests.

Stafford completed 29 of 41 pass attempts for 375 yards and three touchdowns while taking four carries for as many yards in Sunday's 27-20 win over the Colts.

Stafford pulled a vintage performance out of his bag of tricks Sunday, producing a stat line we haven't seen regularly since his prime years in Detroit. The Rams' offense hit the skids in the second half, resulting in a five-drive stretch that produced four consecutive three-and-outs followed by a Kyren Williams' fumble. That's when Stafford took it upon himself to lead an 11-play, 90-yard touchdown drive, immediately following it up with an 88-yard huge play to Tutu Atwell on the ensuing possession to seal the win for Los Angeles. The 37-year-old is proving that he still has plenty left in the tank by throwing for 1,114 yards and eight touchdowns to two interceptions through four starts in 2025. Up next for Stafford is a home matchup on a short week against the 49ers on Thursday Night Football in Week 5.

Purdy completed 22 of 38 pass attempts for 309 yards, two touchdowns and two interceptions while rushing twice for 13 yards in Sunday's 26-21 loss to the Jaguars. He also lost a fumble.

Purdy returned from a two-game absence due to shoulder and toe injuries Sunday, producing mixed results in a failed comeback attempt. The 49ers' quarterback showed no limitations, slinging the ball with ease, and while the three turnovers may be concerning at first glance, his first interception was the result of a bobbled catch attempt while the second was tipped at the line of scrimmage. Despite a depleted group of pass-catchers, Purdy's could deliver similarly gaudy totals in Week 5 as the 49ers attempt to keep up with the Rams' high-powered offense on Thursday Night Football.

Williams completed 22 of 37 pass attempts for 212 yards, one touchdown and one interception while taking eight carries for 13 yards in Sunday's 25-24 win over Las Vegas.

Williams also put two balls on the ground, but he was fortunately able to recover both of his fumbles. The sophomore QB was coming off his best game of the season against the Cowboys, but he reverted to inconsistent form Sunday. We have seen flashes of brilliance from Williams in new head coach Ben Johnson's scheme, but he still isn't polished enough to be relied upon regularly. With the Bears entering their bye, Williams' next action will come in Week 6 on Oct. 13 against the Commanders on Monday Night Football.

Stroud completed 22 of 28 passes for 233 yards, two touchdowns and no interceptions in Sunday's 26-0 win over the Titans. He added four rushes for 11 yards.

Stroud took some time to find his rhythm, totaling only 82 yards on 14 pass attempts before halftime. He looked far more comfortable in the final two quarters, going 12-for-14 for 151 yards with three completions of at least 20 yards, including a 24-yard touchdown pass to Jayden Higgins. While Stroud's final line wasn't outstanding, it was still an encouraging result as he took advantage of a favorable matchup to post season-high marks in touchdowns and passing yardage.

Flacco completed 16 of 34 passes for 184 yards with no touchdowns and two interceptions while adding three rushes for minus-1 yard in the Browns' 34-10 loss to the Lions on Sunday. He also lost a fumble.

Flacco's ragged stat line tells the tale of a tough afternoon against an aggressive Lions defense that sacked him three times in addition to the three turnovers. The veteran signal-caller did keep Cleveland competitive for a significant part of the contest before Detroit pulled away with 14 fourth-quarter points, but with a 2:6 TD:INT and 58.1 percent completion rate through four games, it may not be long before Flacco is swapped out for one of Cleveland's rookie QBs, Dillon Gabriel or Shedeur Sanders. However, Daniel Oyefusi of ESPN.com reports a switch may not yet be in the works just yet, as head coach Kevin Stefanski confirmed after the game he's still not considering a quarterback change.

Mahomes completed 25 of 37 passes for 270 yards, four touchdowns and no interceptions in Sunday's 37-20 win over Baltimore. He added four rushes for five yards.

Mahomes turned in a vintage effort, perhaps not coincidentally as the return of Xavier Worthy reinforced his wide receiver corps. Mahomes threw four touchdowns in a regular-season game for the first time since Week 10 of the 2023 season, with all four scores coming in the red zone. He primarily attempted passes in the short areas of the field but still recorded six completions of at least 15 yards. This was Mahomes' first game with multiple touchdowns this season, and it also accounted for his highest yardage total of 2025. If Worthy's shoulder holds up, Mahomes could be in for much improved results as the campaign progresses -- particularly once Rashee Rice (suspension) is eligible to return in Week 7.

Young completed 18 of 30 passes for 150 yards with one touchdown and no interceptions while adding one rush for three yards in the Panthers' 42-13 loss to the Patriots on Sunday.

Young was pulled late for Andy Dalton in the 29-point defeat, and the third-year signal-caller was largely ineffective most of the afternoon. The highlight of his performance came very early, as Young capped off a crisp seven-play opening possession with a seven-yard touchdown pass to Tommy Tremble. The now 1-3 Panthers will try to capitalize on what should be a favorable matchup against the middling Dolphins defense in a Week 5 home clash next Sunday, but coach Dave Canales' patience with Young may be wearing a bit thin.