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Sean Tucker RB | TB
Buccaneers' Sean Tucker: Likely to be GTD for Week 1
Coach Todd Bowles said Monday that Tucker (undisclosed) will likely be a game-time decision for Sunday's game against the Bengals, Greg Auman of Fox Sports reports.
Tucker did not practice Monday, and the exact nature of his injury isn't known, though the Bucs will be required to provide more clarity with Wednesday's first official injury report of the season. If Tucker is unable to go against Cincinnati, Bucky Irving and Kenny Gainwell should handle most, if not all, of the backfield snaps.
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Sione Vaki RB | DET
Lions' Sione Vaki: Committee approach at RB2
Coach Dan Campbell said Monday that neither Vaki nor Jacob Saylors is viewed as the Lions' strict RB2, and Detroit will use a committee approach behind Jahmyr Gibbs, Nolan Bianchi of The Detroit News reports.
Isiah Pacheco was signed over the offseason to serve as the Lions' RB2 behind Gibbs, but he injured his back and is opening the regular season on injured reserve. Pacheco remains without a firm timetable for return, so it's Vaki and Saylors who will see elevated roles on game days. The inexperienced duo has combined for nine career regular-season carries. Gibbs is expected to have a heavy 2026 workload due to David Montgomery being out of town and now with the Texans.
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TreVeyon Henderson RB | NE
Patriots' TreVeyon Henderson: Not spotted at Monday's practice
Henderson (ankle) was not spotted at the portion of Monday's practice open to the media, according to Mark Daniels of MassLive.com.
Henderson was listed as a non-participant on Sunday's injury report, and it appears likely he will receive the same designation a day later. Henderson has not been ruled out for Wednesday's season opener just yet, but his chances of suiting up are seemingly growing slimmer.
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Jonathon Brooks RB | CAR
Panthers' Jonathon Brooks: Works off to side Monday
Brooks (general soreness) was spotted working out of to the side during Monday's practice, Mike Kaye of ESPN.com reports.
Kaye notes that Brooks was spotted doing some running, so he wasn't completely limited to rehab work. According to Joe Person of The Athletic, Panthers head coach Dave Canales expressed optimism last week that Brooks would be ready to play in Sunday's season opener versus the Bears, and the running back's lack of involvement in Monday's practice isn't believed to have changed the Panthers' stance. Brooks missed the entire 2025 campaign after tearing the ACL in his right knee for the second time in his career in December 2024, but he was fully cleared in the spring and saw action in two preseason games.
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Christian McCaffrey RB | SF
49ers' Christian McCaffrey: Sitting out early drills Monday
McCaffrey (undisclosed) wasn't participating in drills in the early portion of the 49ers' practice early Monday in Australia, Matt Maiocco of NBC Sports Bay Area reports.
Though McCaffrey wasn't on the field for the open portion of practice, it's possible that he fit in some work behind the scenes. San Francisco will post its first injury report of 2026 later Monday, when the extent of McCaffrey's practice participation will be revealed as the 49ers gear up for their season opener against the Rams on Thursday.
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Emanuel Wilson RB | SEA
Seahawks' Emanuel Wilson: Full practice Sunday
Wilson (hamstring) practiced fully Sunday, John Boyle of the Seahawks' official site reports.
Wilson has been a distant third on the RB depth chart behind first-round rookie Jadarian Price and George Holani since the offseason program, and a hamstring injury that was first reported after preseason Week 1 didn't allow Wilson to make any headway for backfield reps to begin the campaign. Now that his health isn't a question, it remains to be seen if Wilson will be a part of the running game during Wednesday's Week 1 matchup with the Patriots.
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TreVeyon Henderson RB | NE
Patriots' TreVeyon Henderson: Misses Sunday's practice
Henderson (ankle) officially didn't practice Sunday, Doug Kyed of the Boston Herald reports.
Henderson suffered a minor right ankle injury Aug. 24 and hasn't been able to practice since then. After Sunday's absence, he'll have two more chances to mix into drills before the Patriots potentially make a ruling on his status for Week 1 when they post Tuesday's injury report. If Henderson isn't able to suit up for Wednesday's season opener at Seattle, Rhamondre Stevenson would be in line to handle the bulk of the backfield reps for New England, with Corey Kiner and practice-squad members Lan Larison and Hassan Haskins the potential candidates for complementary work, per Mike Reiss of ESPN.com.
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TreVeyon Henderson RB | NE
Patriots' TreVeyon Henderson: Looks set to miss Sunday's practice
Henderson (ankle) was in street clothes ahead of Sunday's practice and appears likely to be listed as a non-participant on the Patriots' first injury report of the season, Andrew Callahan of the Boston Herald reports.
New England won't issue its first Week 1 injury report until the conclusion of practice, but unless Henderson is able to fit in some on-field work in the portion of Sunday's session that's closed to the media, he'll go down as a non-participant. After Sunday, Henderson will have two more chances to potentially increase his practice activity before the Patriots decide whether he'll take an injury designation into Wednesday's season opener versus the Seahawks. If Henderson isn't available to play Wednesday or is available only in a limited capacity, the Patriots would likely turn to Rhamondre Stevenson to handle a workhorse role out of the backfield.
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TreVeyon Henderson RB | NE
Patriots' TreVeyon Henderson: Sitting out Saturday's practice
Henderson (ankle) was in street clothes ahead of Saturday's practice, Andrew Callahan of the Boston Herald reports.
Head coach Mike Vrabel suggested earlier Saturday that Henderson could return to practice, but the second-year running back will end up observing the session in street clothes as he continues to recover from an ankle injury. Henderson will have two more chances to return to practice in at least a limited capacity ahead of the Patriots' regular-season opener against the Seahawks on Wednesday.
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TreVeyon Henderson RB | NE
Patriots' TreVeyon Henderson: Could practice Saturday
Henderson (ankle) could return to practice Saturday, Evan Lazar of the Patriots' official site reports.
After missing recent practice time due to an ankle injury, Henderson appears to have at least a chance to get back on the field as New England begins a game-prep stretch ahead of Wednesday's regular-season opener against Seattle. The second-year running back would have to operate in at least a limited capacity over the coming days to have a realistic chance of playing in Week 1. If Henderson cannot play, then Rhamondre Stevenson would be in line for a significant boost in workload, and Corey Kiner would also be in the mix for some backfield touches.