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Nico Hoerner 2B | CHC
Cubs' Nico Hoerner: Likely done for 2021
Hoerner isn't expected to play again this season while he contends with lingering soreness from previous injuries, Gordon Wittenmyer of NBC Sports Chicago reports.
Hoerner hasn't seen the field since Saturday and will sit out a fourth consecutive game Wednesday against the Pirates. Though the Cubs have thus far resisted placing Hoerner on the injured list, he may be available only in an emergency over the team's final five games. Sergio Alcantara will serve as the primary option at shortstop while Hoerner is out.
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Thairo Estrada 2B | BAL
Giants' Thairo Estrada: X-rays negative
Estrada (hand) underwent X-rays that came back negative Wednesday, Susan Slusser of the San Francisco Chronicle reports.
Estrada was hit by a pitch in the seventh inning of Tuesday's matchup against Arizona, but he'll be out of the lineup for Wednesday's game. It's not yet clear whether he'll be available off the bench.
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Josh Rojas 3B | KC
Diamondbacks' Josh Rojas: Riding pine Wednesday
Rojas isn't starting Wednesday's game against the Giants.
Rojas went 1-for-4 with a double, a run, an RBI and a strikeout Tuesday, but he'll head to the bench for the second time in the last three games. Geraldo Perdomo will start at shortstop and bat eighth.
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Andres Gimenez SS | TOR
Indians' Andres Gimenez: Riding pine Wednesday
Gimenez isn't starting Wednesday's game against Kansas City.
Gimenez started each of the last two games and went 3-for-6 with a double and two RBI. Owen Miller will take his place at the keystone and bat seventh.
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Luis Urias 2B | TOR
Brewers' Luis Urias: Idle Wednesday
Urias is out of the lineup for Wednesday's game against the Cardinals.
Urias will head to the bench after he went 2-for-3 with a home run, a walk and two RBI in Tuesday's 6-2 loss. Though he filled in at shortstop Tuesday while Willy Adames nursed a quadriceps injury, Urias is expected to see most of his reps at third base during the rest of the season while Eduardo Escobar serves as the primary replacement at first base for Rowdy Tellez (kneecap).
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Elvis Andrus 2B | ARI
Athletics' Elvis Andrus: Undergoes two procedures
Andrus (lower leg) underwent surgery Wednesday to address a fractured left fibula and to repair a sprain of the the upper ankle.
Andrus' season came to an end over the weekend when he suffered the injury against the Astros, and there wasn't much of a delay before going under the knife. The 33-year-old remains under contract with Oakland next season and is expected to be healthy in time for spring training. He slashed .243/.294/.320 with three homers, 25 doubles, 37 RBI, 60 runs and 12 stolen bases in 146 games during 2021.
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Jeff McNeil 2B | ATH
Mets' Jeff McNeil: Retreats to bench
McNeil isn't starting Wednesday's game against the Marlins.
McNeil will take a seat for the second time in the last three games after he went 0-for-8 with a walk and two strikeouts across his last four appearances. Dominic Smith will start in left field and bat seventh.
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Jahmai Jones DH | BOS
Orioles' Jahmai Jones: Not starting Wednesday
Jones isn't starting Wednesday's game against the Red Sox.
Jones has gone 0-for-5 with a walk and two strikeouts across his last three appearances, and he'll be on the bench for the third time in the last five games. Pat Valaika will shift to second base while Richie Martin starts at shortstop.
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Nico Hoerner 2B | CHC
Cubs' Nico Hoerner: Still not starting
Hoerner (general soreness) isn't starting Wednesday's game against Pittsburgh.
Hoerner has been dealing with general soreness recently and will be out of the lineup for a fourth straight game as a result. It's not yet clear whether he'll return prior to the end of the regular season, but Sergio Alcantara will start at shortstop and bat eighth.
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Santiago Espinal 3B | TEX
Blue Jays' Santiago Espinal: Retains top third base job
Espinal will start at third base and bat eighth Wednesday against the Yankees.
Since being reinstated from the 10-day injured list last weekend, Espinal has started at third base in each of the past four games, going 3-for-13 with two runs. Espinal looks like he'll remain atop the depth chart to close out the regular season, even with Cavan Biggio returning from the IL on Tuesday. Biggio will be on the bench for the second game in a row.