The Astros activated Paredes (hamstring) from the 60-day injured list Friday.

Paredes suffered a torn right hamstring in mid-July that threatened to end his season, but opted to forego surgery in hopes that he could make it back late in the year. He has accomplished that goal, though Paredes is likely not yet 100 percent and will be asked to take it easy on the basepaths. With Yordan Alvarez (ankle) landing on the 10-day injured list, Paredes will step into the Astros' designated hitter role.

House is out of the lineup for Friday's game against the Mets, Mark Zuckerman of MASNSports.com reports.

House will yield to Paul DeJong at third base Friday after making three consecutive starts at the position. House is 9-for-43 (.209) with two home runs in September.

Harris is not in the lineup for Friday's game in Pittsburgh.

After starting three straight games at third base earlier this week, Harris has now been held out of the lineup in back-to-back contests. Darell Hernaiz will play the hot corner and Zack Gelof will handle second base in Friday's series opener. Harris and Gelof could continue to form a quasi-platoon down the stretch, though it will be difficult to know ahead of time which of the two of them is going to start since they both bat from the right side of the plate.

Hayes (back) will start at third base and bat seventh in Friday's game versus the Cubs.

Hayes didn't start the previous two tilts due to a back issue, but he entered Thursday's game against the Cubs as a defensive replacement and is back in the lineup Friday. The 28-year-old enters play Friday having gone hitless over his last five contests.

The Astros will reinstate Paredes (hamstring) from the 60-day injured list ahead of Friday's game against the Mariners, Brian McTaggart of MLB.com reports.

Paredes strained his hamstring in mid-July, but bypassed surgery in hopes of returning late in the 2025 season. The decision will pay off Friday, as he's slated to come off the injured list in time for a three-game set against the Mariners, who are tied with Houston atop the AL West. Paredes will be used as a designated hitter once reinstated, and he may be asked to run less than full speed on the basepaths. Still, it's a significant boost to the Astros' lineup. He slashed .259/.359/.470 with 19 home runs, 51 runs and 50 RBI in 409 plate appearances before sustaining the injury.

Ramirez went 2-for-5 with a home run and two RBI in Thursday's 3-1 win over the Tigers.

Ramirez provided the decisive blow in the seventh inning with a two-run homer into the right field stands at Comerica Park, completing Cleveland's sweep of the first-place Tigers. The streaky Guardians, which have won seven in a row, are now 3.5 games back in the AL Central and 1.5 out of a wild card. The home run was the 29th for Ramirez, who also has 80 RBI, 39 steals and 96 runs scored over 148 contests.

Hayes missed the last two games due to back soreness, Mike Petraglia of MLB.com reports. He did enter Thursday's 1-0 win over the Cubs as a defensive replacement in the ninth inning.

The back issue, which has bothered Hayes previously, cropped up during the Reds' series this week against the Cardinals. Cincinnati manager Terry Francona tried to get him time off then, but Spencer Steer came down with a neck injury. With Steer now back, Hayes can rest up. Francona said the third baseman, who's been managing the pain, could visit with a specialist by Monday. Sal Stewart served as the third baseman the last two games and presumably will continue to get the nod if Hayes misses more time.

Moncada (ankle) isn't in the lineup for Thursday's game against the Brewers, Rhett Bollinger of MLB.com reports.

Thursday will mark the third consecutive start Moncada has missed since tweaking his ankle during Sunday's contest. His absence will allow Luis Rengifo to make another start at third base and bat fifth.

Hayes isn't in the lineup for Thursday's game against the Cubs.

Hayes will get a second straight day to rest after going 0-for-13 in his last four games. Sal Stewart will get the nod at third base instead, opening up first base for Spencer Steer.

Caminero (back tightness) is not in Thursday's lineup against the Blue Jays.

He exited Wednesday's game with back tightness and is still ailing Thursday. Tristan Gray is starting at third base and batting sixth.