Smith (quadriceps) is likely to be placed on the 10-day injured list ahead of Friday's series opener against the Dodgers, Steve Gilbert of MLB.com reports.

Smith was removed from Wednesday's win over the Brewers due to left quad tightness. He won't stick around in Milwaukee for Thursday's series finale and will instead head back to Phoenix to undergo imaging. Assuming the MRI confirms a quad strain, Smith will likely require a stint on the IL. Tyler Locklear will start at first base Thursday and should serve as the Diamondbacks' primary option at the position while Smith is shelved.

Yelich is out of the lineup for Thursday's game against the Diamondbacks.

With Milwaukee wrapping up its series against Arizona with a day game after a night game, Yelich will receive a breather after he had started in each of the last 17 contests. Yelich's absence will clear the way for William Contreras to get a break from catching yet remain in the lineup as Milwaukee's designated hitter.

Alvarez is out of the lineup for Thursday's contest against the Rockies, Matt Kawahara of the Houston Chronicle reports.

Alvarez started in both of the past two days upon his return from the 60-day injured list, but he will get a breather for Thursday's matinee. Jose Altuve will occupy the designated-hitter spot and Mauricio Dubon will cover left field in the rubber match.

McCutchen is absent from the lineup for Thursday's tilt in St. Louis.

McCutchen will get a routine day off after starting in the previous two games and five of the last six contests. Bryan Reynolds will serve as the Pirates' designated hitter Thursday, while Jack Suwinski will man right field.

Smith (quadriceps) is out of the lineup for Thursday's game against the Brewers.

After exiting early in Wednesday's 3-2 win due to left quad tightness, Smith will take a seat for Thursday's matinee contest. The Diamondbacks seem to be classifying Smith as day-to-day, and even if he had emerged from Wednesday's contest without an injury, he likely would have been in line to sit Thursday since the Brewers are sending a lefty starter (Jose Quintana) to the bump. Tyler Locklear will get the nod at first base in the series finale.

Manzardo started at DH and went 1-for-5 with an RBI in Wednesday's 4-3 extra-inning win over the Rays.

Manzardo delivered a run-scoring single in the bottom of the 10th inning, as Cleveland walked off Tampa Bay for its second consecutive win. Manzardo's had a hand in each, knocking in the game-winning run in both victories. With the Guardians moving on from Carlos Santana, who was placed on outright waivers Tuesday, Manzardo is poised for regular playing time through the end of the season.

Devers went 4-for-4 with a pair of home runs, a double, a walk, four total runs and five total RBI in a 12-3 victory versus the Cubs on Wednesay.

Devers ignited San Francisco's offense early with a first-inning solo blast. He added a run-scoring double in the third and a three-run homer in the sixth. Devers finished with his fourth four-hit game of the campaign, and his five RBI trailed only his May 23 eight-RBI performance against the Orioles for his most this season. In fact, Devers tallied more RBI on Wednesday than he had in his previous 15 games combined.

Ohtani (1-1) earned the win over Cincinnati on Wednesday, allowing one run on two hits and two walks while striking out nine batters over five innings.

Ohtani gave up a solo homer to Noelvi Marte in the third inning, but the Reds otherwise weren't able to do much against him. The two-way star got 14 whiffs on his 87 pitches and fanned a season-high nine batters. Of note, Ohtani threw 23 curveballs Wednesday -- per Jack Harris of the Los Angeles Times, which blew away his previous career-high total of 16. It's equally important that Ohtani was allowed to finish the fifth inning -- it was the first time this season he's gone that deep, which by rule means it's the first time he was able to qualify for a victory. That's a significant development for fantasy managers, as the Japanese superstar should be able to help in that category moving forward while potentially building upon his already impressive 44:7 K:BB through 32.1 frames.

Pederson went 2-for-6 with a three-run home run, two additional RBI and two additional runs scored during Wednesday's 20-3 win over the Angels.

Pederson lifted his fifth home run of August with a three-run blast off Jack Kochanowicz in the second inning and extended his hit streak to seven games. The 33-year-old slugger set season highs in runs scored and RBI during the offensive outburst. His previous best RBI total was two. During his hit streak, Pederson has gone 9-for-28 (.321) with nine RBI and five runs scored.

Alvarez went 1-for-2 with a two-run home run and an additional run scored during Wednesday's 4-0 win over Colorado.

Alvarez was activated from the injured list ahead of Tuesday's series opener and went hitless with two walks in four plate appearances in his return. He walked twice more Wednesday and delivered his first hit since coming back by launching a two-run home run off Angel Chivilli in the fourth inning. Alvarez slashed .210/.306/.340 with three home runs across 121 plate appearances before being placed on the injured list back in May.