The Athletics optioned Lopez to Triple-A Las Vegas on Wednesday.

While making a spot start Tuesday against the Rangers, Lopez was touched up for three runs on six hits and four walks in 2.2 innings. He wasn't going to be available for a few days, so the Athletics will replace him on the 26-man active roster with a fresh bullpen arm in Carlos Duran, who was called up from Triple-A.

Rodriguez will serve as the Blue Jays' opening pitcher in Wednesday's game against the Red Sox, Mitch Bannon of The Athletic reports.

Rodriguez was used as a starting pitcher by Toronto last season, but he's worked exclusively in relief in 2025. He hasn't thrown more than two innings in any appearance and will be pitching on two days' rest, so he should be in line for a fairly abbreviated outing. Eric Lauer is likely to follow him in bulk relief.

The White Sox optioned Gilbert to Triple-A Charlotte on Wednesday.

Gilbert allowed one run across two innings of work in an opener assignment Tuesday versus the Brewers and will now head to the minors. Fraser Ellard (hamstring) is back from the 15-day injured list to absorb Gilbert's roster spot.

The White Sox activated Ellard (hamstring) from the 15-day injured list Wednesday.

Ellard missed almost three weeks of action due to a strained right hamstring. The left-handed reliever should go back to working in high-leverage situations in an unsettled White Sox bullpen.

The Blue Jays designated Lawrence for assignment Wednesday.

Lawrence helped save the bullpen with 2.2 innings in Tuesday's loss to the Red Sox, but he's being sent packing after just one day on the active roster. Eric Lauer was called up from Triple-A Buffalo in a corresponding move and is expected to either start or serve as a bulk reliever in Wednesday's game against Boston.

Shaw signed a minor-league contract with the Mariners on Tuesday and was assigned to Triple-A Tacoma.

He made his organizational debut Tuesday, recording one out while allowing one earned run on one hit and three walks in Tacoma's 5-4 loss to Las Vegas. The 37-year-old right-hander has a long track record of success as a setup man in the big leagues, but he made just five appearances in the majors in 2024 and struggled with the Reds in spring training and during the early part of the minor-league season at Triple-A Louisville before Cincinnati released him earlier this month.

The Mariners designated Lao for assignment Wednesday.

The transaction frees a spot on the 40-man roster for outfielder Rhylan Thomas, whose contract was selected from Triple-A Tacoma. Lao allowed one unearned run with a 3:0 K:BB over a 1.2-inning relief appearance earlier this month in what was his major-league debut.

The Red Sox will place Bernardino on the bereavement list prior to Wednesday's game in Toronto, Chris Cotillo of MassLive.com reports.

It will be the corresponding move for Lucas Giolito (hamstring), who will come off the 15-day injured list to start Wednesday's contest. By rule, Bernardino will miss the next 3-to-7 games.

The Astros placed Abreu on the paternity list Wednesday.

Abreu will be away from the Astros for between one and three games while he welcomes a new addition to his family. He'll temporarily cede his spot on the 26-man active roster to right-hander AJ Blubaugh, who was called up from Triple-A Sugar Land ahead of his first MLB start Wednesday against the Tigers.

The Royals optioned Bowlan to Triple-A Omaha on Wednesday.

Bowlan has turned in one scoreless appearance with the big club this season. He's clearing out to make room on the roster for Noah Cameron, who is making a spot start Wednesday.