Purdy (toe) practiced in full Thursday, Matt Barrows of The Athletic reports. Afterward, coach Kyle Shanahan announced on KNBR San Francisco that Purdy was in line to start Sunday's contest at Arizona.

Purdy thus is poised for his first game action since Week 4 and just his third appearance of the season due to a nagging turf toe injury. He spoke on the issue Thursday, saying that surgery never was on the table, and that he also doesn't intend to wear a steel insert in his cleats, per Matt Barrows of The Athletic. Purdy also told Nick Wagoner of ESPN.com that he'll start this weekend, assuming he gets through the next few days unscathed. "I feel really good," Purdy said. "I feel healthy and excited to be back and ready to go and lead the guys. I'm really excited about this week." Purdy will retake the reins of the 49ers offense from No. 2 QB Mac Jones, who has handled eight spot starts this season.

DeVito (coach's decision) is inactive but will serve as the Patriots' emergency third quarterback against the Jets on Thursday.

DeVito has yet to appear in a regular-season game as New England's emergency QB3 behind Drake Maye and Joshua Dobbs. DeVito is restricted from playing Thursday unless both Maye and Dobbs are removed from the game due to injury, illness or ejection.

Smith (quadriceps) isn't listed on the Raiders' Week 11 injury report.

Per Tom Pelissero of NFL Network, Smith suffered a thigh bruise last Thursday against the Broncos, but the issue was downplayed afterward by coach Pete Carroll. With Smith not listed on this Thursday's injury report, the QB will be good to go Monday night against the 3-5-1 Cowboys, who have dropped two straight contests, most recently a 27-17 loss to the Cardinals in Week 9 in which Jacoby Brissett completed 21 of 31 pass attempts for 261 yards and two touchdowns, while logging five carries for four yards and a rushing score.

Coach Kyle Shanahan said on the 49ers Game Plan on Thursday that Purdy (toe) is slated to start Sunday's game at Arizona, Matt Maiocco of NBC Sports Bay Area reports.

Per David Lombardi of SFStandard.com, Shanahan has hinted at this possibility this week but added that the 49ers "want three aggressive practices, and we want to hear from him and make sure he feels good after them, too." Purdy remained limited at Wednesday's practice, but after Thursday's session, offensive coordinator Klay Kubiak told Cam Inman of The San Jose Mercury News that the fourth-year pro has done more this week than in previous weeks and looks more confident in his movements after contending with a turf toe injury for much of the campaign. Shanahan likely will make the announcement of Purdy returning to the starting lineup for the first time since Week 4 public at some point before week's end.

Smith (quadriceps) is participating in practice Thursday, Levi Edwards of the Raiders' official site reports.

Smith is dealing with a quad contusion sustained during Las Vegas' loss to the Broncos on Thursday Night Football in Week 10, so for him to be handling even limited practice reps is a positive sign. Thursday's official practice report will disclose Geno's activity level as he prepares to ramp up for a home matchup against the Cowboys on Monday night. At this stage, there doesn't appear to be serious reason for concern about Smith's availability.

Flacco (shoulder) was a limited participant in practice Thursday, Paul Dehner Jr. of The Athletic reports.

Flacco officially went down as a non-participant Wednesday, so Thursday's limited participation is a step in the right direction. The veteran quarterback is expected to start Cincinnati's next two games, Sunday at Pittsburgh and Week 12 against the Patriots, as Joe Burrow (toe) is targeting Thanksgiving Day against the Ravens as his return date. Flacco played through his shoulder injury and threw for 470 yards in Week 9 against the Bears prior to Cincinnati's Week 10 bye.

Jackson (knee) returned to a full practice Thursday.

Jackson was deemed a 'DNP' on Wednesday due to knee soreness, but a day later he was able to work fully and moved around well in the process, per Jamison Hensley of ESPN.com, which paves the way for Jackson to play Sunday against the Browns. In his last outing, the star QB completed 17 of his 29 pass attempts for 176 yards with a touchdown, while adding nine carries for 36 yards in the Ravens' Week 10 win over the Vikings.

McCarthy (right hand) practiced fully Thursday.

McCarthy opened Week 11 prep Wednesday as limited due to a right hand injury, which stemmed from hitting it on the helmet of a Ravens defender while following through on a throw this past Sunday. He's been wearing padding on the hand in question in practice this week, but on Thursday he was able to take snaps under center and also attempt passes, per Kevin Seifert of ESPN.com. McCarthy's ensuing listing of full indicates that he's good to go ahead of Sunday's game versus the Bears.

Mills will start Sunday's road contest against the Titans with C.J. Stroud (concussion) having been ruled out Thursday, Adam Schefter of ESPN reports.

Mills will draw at least one more start while Stroud works his way through the concussion protocol, and he could find himself in a similar position Week 12, when the Texans will face a short week of preparation before taking on the Bills on Thursday Night Football. After compiling 312 total yards and three touchdowns during Houston's comeback win over the Jaguars in Week 12, Mills has made a case for himself as a fantasy option for QB-needy teams, especially in deeper formats.

The Texans announced Thursday that Stroud (concussion) has been ruled out for Sunday's game against the Titans, leaving Davis Mills in position to draw another start, Adam Schefter of ESPN reports.

Stroud will miss a second consecutive game as he continues to work his way through the NFL's concussion protocol. He has yet to resume practicing, and per Aaron Wilson of KPRC 2 Houston is still experiencing symptoms. Stroud's next chance to play will come Week 12 versus the Bills on Thursday Night Football, but before being eligible to retake the field he'll need to fully clear the concussion protocol, which includes undergoing evaluation by an independent neurologist.