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Brayden Willis TE | SF
49ers' Brayden Willis: Bumps to active roster
The 49ers signed Willis to the active roster from the practice squad Wednesday.
Willis takes the roster spot of Ben Bartch, whom San Francisco placed on IR on Wednesday. With George Kittle (hamstring) also on IR until at least Week 6, Willis is positioned to contribute in a reserve role at tight end versus the Cardinals on Sunday and beyond.
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Tyler Warren TE | IND
Colts' Tyler Warren: Doesn't practice Wednesday
Warren (toe) didn't practice Wednesday.
Warren logged a 93 percent snap share in Sunday's 29-28 win over the Broncos, but the tight end's absence from Wednesday's practice makes his status worth monitoring as this weekend's game against the Titans approaches. Through his first two regular-season games, the 2025 first rounder has combined for 11 catches (on 16 targets) for 155 yards.
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Jauan Jennings WR | MIN
49ers' Jauan Jennings: Limited Wednesday
Jennings (shoulder/ankle) will be limited at practice Wednesday, Cam Inman of The San Jose Mercury News reports.
Jennings exited a season-opening win at Seattle due to a left shoulder injury that capped him to one limited session during Week 2 prep. He was able to suit up this past Sunday in New Orleans and take on an 87 percent snap share on his way to five catches (on 10 targets) for 89 yards and one touchdown while working with fill-in starting quarterback Mac Jones. Jennings will be joined as a limited participant Wednesday by No. 1 signal-caller Brock Purdy (toe/left shoulder), who has a chance to return to action this Sunday versus the Cardinals, as coach Kyle Shanahan told Nick Wagoner of ESPN.com on Wednesday. As a result, the potential exists for Jennings to have his most familiar quarterback under center Week 3, assuming the wide receiver is able to play through his shoulder and ankle issues.
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Josh Downs WR | KC
Colts' Josh Downs: Not practicing due to ankle injury
Downs (ankle) didn't practice Wednesday.
It's perhaps unexpected, given that Downs' workload improved from Week 1 to Week 2, although his snap share (60 percent) and route share (63 percent) were still low relative to last year's numbers. He's getting the ball when he's on the field, at least, with a target on 31 percent of his routes for the season after finishing Sunday's win over Denver with a team-high eight targets. If Downs can't play this weekend at Tennessee, the Colts have Adonai Mitchell and Ashton Dulin as their top backups at wide receiver. Both would project for lower target rates than Downs, which would mean slightly higher rates for Tyler Warren and Michael Pittman.
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Darius Slayton WR | IND
Giants' Darius Slayton: Limited in practice
Slayton (groin/calf) was a limited participant in Wednesday's practice, Dan Salomone of the Giants' official site reports.
Slayton has played all but one of the Giants' offensive snaps through two weeks this season, though in that span he's brought in just two catches for 61 yards on five targets, with all of his production having come during Week 2's overtime loss to the Cowboys. While Slayton being limited Wednesday doesn't yet seem an indication that his status is genuinely in jeopardy for Sunday night's matchup against the Chiefs, he appears definitively positioned behind both Wan'Dale Robinson and superstar Malik Nabers in New York's wide receiver pecking order.
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Brock Purdy QB | SF
49ers' Brock Purdy: In line for limited practice
Coach Kyle Shanahan said Purdy (toe/shoulder) will be limited at Wednesday's practice, Eric Branch of the San Francisco Chronicle reports.
Purdy emerged from a Week 1 win at Seattle with a turf toe variant, which sidelined him this past Sunday in New Orleans. As the 49ers begin preparations for Sunday's home opener against the Cardinals, Shanahan is giving Purdy "a chance" to return to action, even as the emergency third quarterback, per Nick Wagoner of ESPN.com. As a result, it appears Purdy and fill-in Week 2 starter Mac Jones are in consideration to lead San Francisco's offense Week 3.
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Jordan Mason RB | MIN
Vikings' Jordan Mason: Primed for large workloads
Mason is taking over as Minnesota's unquestioned lead back with Aaron Jones (hamstring) going to injured reserve and missing at least four games.
With No. 3 RB Ty Chandler (knee) already on IR, the Vikings are left with Mason and Zavier Scott as their only running backs on the active roster. The team figures to promote Cam Akers or Xazavian Valladay from the practice squad before Sunday's game against Cincinnati, but that shouldn't stop Mason from taking on a large workload against a vulnerable defense in a game featuring two backup quarterbacks. Vikings coach Kevin O'Connell told reporters Wednesday that Mason is a "potential bell-cow kind of back."
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Wan'Dale Robinson WR | TEN
Giants' Wan'Dale Robinson: Tending to foot issue
Robinson was a limited practice participant Wednesday due to a foot injury, Dan Salomone of the Giants' official site reports.
Robinson dealt with an ankle issue last week and now is tending to a new health concern as the Giants prep for Sunday's matchup with the Chiefs. During a Week 2 back-and-forth overtime loss at Dallas, Robinson handled a 70 percent snap share and reeled off eight catches (on 10 targets) for 142 yards and one touchdown, all of which were surpassed by No. 1 WR Malik Nabers' 9-167-2 line on 13 targets.
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Tyrone Tracy Jr. RB | NYG
Giants' Tyrone Tracy: Dealing with chest issue
Tracy was limited at Wednesday's practice due to a calf injury, Dan Salomone of the Giants' official site reports.
After handling a 74 percent snap share during a Week 1 loss at Washington, Tracy fell all the way back to 42 percent in Sunday's loss in Dallas, while rookie Cam Skattebo jumped from 12 percent in the season opener to 52 percent Week 2. The result: Tracy recorded nine touches for 51 yards from scrimmage, and Skattebo had 13 touches for 59 total yards Sunday. Tracy's dip in usage may have been attributed to a health concern, and now his status will be one to monitor ahead of a Week 3 matchup with the Chiefs.
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Jayden Daniels QB | WAS
Commanders' Jayden Daniels: No practice Wednesday or Thursday
Daniels (knee) won't practice any earlier than Friday this week, Jeff McLane of The Philadelphia Inquirer reports.
Commanders coach Dan Quinn said Daniels won't practice Wednesday or Thursday, instead focusing on rehab for the knee sprain he suffered last Thursday in Green Bay. The extra time off in between games helps his cause, but Daniels nonetheless appears in danger of missing Sunday's game against Las Vegas. Marcus Mariota will get the start at QB if Daniels doesn't.