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Marcus Semien 2B | NYM
Mets' Marcus Semien: Receiving night off
Semien is out of the lineup for Wednesday's game against Atlanta.
The Mets will give Semien a breather after he started in each of the last 10 games while slashing .222/.310/.417 with two home runs, one steal, six RBI and six runs during that stretch. Brett Baty will replace Semien at second base and will bat eighth.
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Anthony Seigler 2B | BOS
Red Sox's Anthony Seigler: Shifts back into reserve role
Seigler is out of the lineup for Wednesday's game against the Blue Jays.
Seigler is back on the bench for a second straight day while the Red Sox go with Nick Sogard at second base. Prior to Tuesday, Seigler had covered the keystone in four of the Red Sox's previous five contests, but his uptick in playing time appears to have been mostly the result of Willson Contreras and Masataka Yoshida missing out on two starts apiece due to illness.
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Tommy Edman 2B | LAD
Dodgers' Tommy Edman: Not in Wednesday's lineup
Edman is not in the Dodgers' starting lineup against the Royals on Wednesday.
Edman will be on the bench for the start of Wednesday's game after going 2-for-8 with a run scored across the first two games of the series against Kansas City. Miguel Rojas will start at second base and bat ninth in Edman's absence.
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Zach McKinstry RF | DET
Tigers' Zach McKinstry: Idle against southpaw
McKinstry is out of the lineup for Wednesday's game against the Guardians.
The Tigers will keep McKinstry on the bench along with fellow left-handed hitter Colt Keith while southpaw Foster Griffin takes the hill for the Guardians. Corey Julks was called up from Triple-A Toledo on Wednesday and will step in for McKinstry in right field in his Tigers debut.
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Travis Bazzana 2B | CLE
Guardians' Travis Bazzana: Sitting against lefty again
Bazzana is out of the lineup for Wednesday's game against the Tigers.
The left-handed-hitting Bazzana will be left out of the lineup for the second time in the Guardians' last three matchups versus a left-handed starting pitcher. Angel Genao will fill in at second base for Bazzana, who is slashing just .192/.306/.240 (65 wRC+) over 121 plate appearances versus same-handed pitching this season.
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Chase Meidroth 2B | CHW
White Sox's Chase Meidroth: Making return to starting nine
Meidroth (wrist) will start at shortstop and bat sixth in Wednesday's game against the Reds.
With the discomfort in his left wrist having subsided, Meidroth will check back into the starting nine after he had been relegated to a bench role for the White Sox's previous two contests. Meidroth will pick up a start at shortstop for the first time all season while the White Sox's main option at that position, Colson Montgomery, slides over to third base to fill in for a resting Miguel Vargas.
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Brice Turang 2B | MIL
Brewers' Brice Turang: Included in lineup in series finale
Turang (thumb) will start at second base and bat second in Wednesday's game against the Padres, Adam McCalvy of MLB.com reports.
Turang played the entirety of Tuesday's 11-2 loss before Brewers manager Pat Murphy revealed after the contest that the infielder had been dealing with a sprained thumb. According to McCalvy, Murphy issued a retraction when he spoke to the media Wednesday, noting that he meant outfielder Jackson Chourio had been playing through the thumb issue rather than Turang. With that in mind, fantasy managers should have no reservations about including Turang in lineups while he's staged an impressive follow-up to his breakout 2025 campaign. He'll head into Wednesday's contest with a .269 average, 16 home runs, 16 stolen bases, 75 RBI and 74 runs through 114 games.
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Jeff McNeil 2B | ATH
Athletics' Jeff McNeil: Idle for series finale
McNeil is out of the lineup for Wednesday's game against the Rays.
McNeil will take a seat for the series finale after he had started in each of the previous three contests and served as the Athletics' table setter in the past two games. Tommy White will fill in for McNeil at first base Wednesday, while shortstop Donovan Walton receives a look out of the leadoff spot.
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Jose Altuve 2B | HOU
Astros' Jose Altuve: Absent from Houston lineup
Altuve (foot) is out of the lineup for Wednesday's tilt in San Francisco.
Altuve departed Tuesday's 4-1 loss after being hit on the left foot by a pitch. Astros manager Joe Espada said Wednesday that Altuve remains sore and will be evaluated by team doctors when the team returns home this weekend, according to Matt Kawahara of the Houston Chronicle. Nick Allen will fill in for Altuve at second base Wednesday.
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Bryson Stott 2B | PHI
Phillies' Bryson Stott: Settling in at third base
Stott will start at third base and bat fifth in Wednesday's game against the Cardinals.
Stott will carry a four-game hitting streak into Wednesday's contest and has been sizzling at the dish throughout August, slashing .424/.587/.545 with four doubles, five stolen bases, 13 walks, seven runs and four RBI in 11 contests. He'll also be making his ninth consecutive start at third base, where he'll continue to see most of his reps moving forward after the Phillies acquired Luis Arraez last week and installed him as their everyday second baseman. Stott looks poised to head into 2027 carrying eligibility at both second and third base in the majority of fantasy leagues.