Mayo is out of the lineup for Friday's game against the Pirates, Roch Kubatko of MASNSports.com reports.

Mayo started the first four games of the season but finds himself on the bench Friday for the second time in Baltimore's past three contests. The 24-year-old has gone 2-for-17 with a double, a stolen base, three walks and seven strikeouts in 20 plate appearances. Blaze Alexander and Jeremiah Jackson, who have been splitting time at second base, are both in the lineup Friday, with Alexander at the hot corner and Jackson at the keystone.

Keith is not in the lineup for Friday's game versus the Cardinals.

It's a routine breather for Keith, who sports a healthy .962 OPS in the early going this season. Gleyber Torres is getting a start in the designated hitter slot and Zach McKinstry will cover second base for the Tigers.

Durbin went 0-for-4 with two strikeouts in Wednesday's 6-4 loss to Houston.

Durbin is one of many Red Sox hitters to have stumbled out of the gate. Following a fifth consecutive hitless performance, Boston's primary third baseman is 0-for-18 with five strikeouts and one walk.

Jung went 2-for-4 with an RBI in Wednesday's 8-3 loss to Baltimore.

Jung, who returned to the lineup after a getting a day off Tuesday, logged his first hits of the season and drove in his first run. He was hitless over his first 18 at-bats before a run-scoring single in the fourth inning. Tuesday's rest day may have been the ticket for Jung, who registered three hard-hit batted-ball events, per Statcast.

Ramirez went 1-for-3 with a two-run home run and a walk in Wednesday's 4-1 win over the Dodgers.

Ramirez is still looking for his first multi-hit effort of the campaign, but he was able to swat his first homer Wednesday to give the Guardians some breathing room in the eighth inning. The third baseman has added two doubles, five RBI, two stolen bases and two runs scored over seven games this season. Ramirez is hitting just .143 so far, but he's faced strong pitching staffs in the first two series of Cleveland's season. It shouldn't be long before he locks in as a well-rounded force at the plate and on the basepaths.

McKinstry is out of the lineup for Wednesday's game against the Diamondbacks.

McKinstry had started in three of the Tigers' last four matchups against right-handed pitchers, but he'll take a seat Wednesday against righty Zac Gallen. The final spot in Detroit's everyday lineup versus righties looks like it could come down to McKinstry and Javier Baez, but neither player has done much in the early going to take control of a regular role. McKinstry has gone 1-for-8 with three strikeouts thus far, while Baez has two hits in 11 at-bats.

McMahon is not in the lineup for Wednesday's game against the Mariners.

The Yankees are facing a righty in George Kirby, but the left-handed-hitting McMahon will nonetheless begin the game on the bench. Amed Rosario is at third base and batting seventh in Wednesday's series finale.

Smith went 2-for-3 with a solo home run and a walk in Tuesday's 9-2 win over the Red Sox.

Smith took Jovani Moran deep in the seventh inning for his first home run of the season. Smith entered play Tuesday with just two hits in 21 trips to the plate, but he's now reached base five times over the last two games and has drawn five walks in six games this season after walking just 8.7 percent of the time in 2025. Smith is competing for at-bats with Jake Meyers, Joey Loperfido and Brice Matthews in the Houston outfield, but the Astros want Smith to take hold of right field.

Durbin is out of the lineup for Tuesday's game against the Astros, Chris Cotillo of MassLive.com reports.

Durbin is hitless through the first four contests of the season and will get a game to reset Tuesday in Houston. Andruw Monasterio will step in at the hot corner and bat sixth for Boston against Astros righty Hunter Brown.

Moncada is not in the lineup for Tuesday's contest against the Cubs.

Moncada homered in Monday's loss to the Cubs, but he'll receive his first day off of the season Tuesday as the Angels look to even the series. Jeimer Candelario will cover third base and bat fifth for the Halos.