Penix completed 27 of 42 passes for 298 yards with a touchdown and no interceptions and rushed six times for 21 yards and another score in the Falcons' 23-20 loss to the Buccaneers on Sunday. He also committed a fumble recovered by Atlanta.

Penix opened his first full season as a starter in fine fashion, looking poised and in command against a veteran, aggressive Buccaneers defense for most of the afternoon. The southpaw signal-caller leveraged Bijan Robinson's elite yards-after-catch skills on the opening drive, hitting his star running back for a 50-yard catch-and-run touchdown. Penix would go on to cap off an 18-play, 91-yard marathon drive in the fourth quarter with a four-yard touchdown run, and he then drove the Falcons a total of 60 yards in eight plays to put them in position for a would-be game-tying field goal that Younghoe Koo couldn't convert. Penix also lost Drake London to a shoulder injury for that final drive, and it remains to be seen if he'll have his top target available for a Week 2 road showdown with the Vikings next Sunday night.

Jones completed 22 of 29 passes for 272 yards with a touchdown and no interceptions and added seven rushes for 26 yards and two more scores in the Colts' 33-8 win over the Dolphins on Sunday.

Jones opened the game hot and never looked back, leading the Colts to a field goal on his first regular-season possession as the team's quarterback while recording four completions on that drive. Jones was near perfect the rest of the way as well, and he connected with Michael Pittman for a 27-yard strike on his one scoring toss while also displaying plenty of chemistry with rookie first-round pick Tyler Warren (seven receptions). Jones also added his trademark rushing contributions with a pair of one-yard scoring runs, but he and the rest of the team's air attack get a big step up in competition when the Broncos come to town for a Week 2 matchup next Sunday.

Lawrence completed 19 of 31 passes for 178 yards and a touchdown with one interception in Sunday's 26-10 win over the Panthers.

It was an odd game that saw the Jaguars take a 20-3 lead into halftime, but only after a lengthy weather delay in the middle of the second quarter due to lightning. Whether that delay impacted Lawrence's performance is tough to say, but he didn't need to do much in the second half. New coach Liam Coen led Baker Mayfield to a career-best season with the Buccaneers in 2024, and while he could eventually do the same for Lawrence, the jury is very much still out. Lawrence will look to deliver better numbers on the road Week 2 in what could be a barn burner against Joe Burrow and the Bengals.

Maye completed 30 of 46 passes for 287 yards with a touchdown and an interception and added four rushes for 11 yards in the Patriots' 20-13 loss to the Raiders on Sunday. He also committed a fumble recovered by New England.

Beginning what is to be his first full season as a starter, Maye fought an uphill battle for most of the afternoon in a game where the Patriots found themselves down 7-0 after the opening possession. He would ultimately help keep New England competitive with a two-yard touchdown toss to DeMario Douglas to knot the score at 7-7 later in the first quarter, and he would also lead a late 10-play drive that would culminate in a field goal and put New England within seven points. Maye did an excellent job spreading the ball around by recording completions to nine different pass catchers, and he'll head into a Week 2 divisional road battle against what was a generous Dolphins secondary in Week 1 with plenty of momentum.

Rattler completed 27 of 46 passes for 214 yards in Sunday's 20-13 loss to the Cardinals. He added 29 rushing yards on four carries.

The second-year QB didn't commit a turnover, but that was about the only silver lining to his Week 1 performance. Rattler attempted a career-high 46 passes in his first game in new coach Kellen Moore's scheme despite the fact that the score was fairly close all the way through, but his 4.7 yards per attempt was poor. With Tyler Shough waiting in the wings, Rattler may need to improve his numbers quickly to keep his starting job, beginning with a Week 2 home tilt against the 49ers.

Smith completed 24 of 34 passes for 362 yards with a touchdown and an interception while adding two rushes for 10 yards in the Raiders' 20-13 win over the Patriots on Sunday.

The veteran signal-caller looked right at home in a Raiders uniform from the opening possession, which he capped off with perfect 26-yard scoring strike to Tre Tucker. While that would be Smith's only touchdown toss of the game, he would pile up a fantasy-friendly yardage total by connecting with seven different pass catchers, including a trio of rookies in Dont'e Thornton, Jack Bech and Ashton Jeanty. Smith also displayed excellent chemistry with star tight end Brock Bowers, but the latter notably exited the game in the second half with a knee injury. Tom Pelissero of NFL Network reports Bowers downplayed the injury after the contest and stated he wanted to return to the game, so Smith appears to have a good chance of having access to his top target for a Week 2 AFC West home showdown against the Chargers on Monday night, Sept. 15.

Wilson completed 17 of 37 passes for 168 yards, no touchdowns and no interceptions in Sunday's 21-6 loss to the Commanders. He also rushed eight times for 44 yards.

Wilson had just 58 yards on 15 first-half pass attempts, and he wasn't significantly more efficient after halftime, finishing the game with just 4.5 yards per pass attempt while the Giants failed to score a touchdown. He didn't get much help from the running game behind a poor offensive line, as Wilson led the team in rushing yards while Tyrone Tracy, Devin Singletary and Cam Skattebo combined to rush for only 30 yards on 15 carries. If Wilson doesn't improve Week 2 against the Cowboys, it may not be long until the Giants turn to rookie first-round pick Jaxson Dart over the declining veteran.

Mayfield completed 17 of 32 passes for 167 yards with three touchdowns and no interceptions while adding five rushes for 39 yards in the Buccaneers' 23-20 win over the Falcons on Sunday.

Mayfield was considerably less efficient than usual while facing a feisty Falcons defense in a rowdy dome environment, but after some early struggles, the veteran signal-caller was able to awaken the Buccaneers offense with a 30-yard scoring strike to rookie Emeka Egbuka. Mayfield would subsequently connect with Bucky Irving from nine yards out in the third quarter, and he capped off what turned out to be a rewarding fantasy day with a critical 25-yard touchdown toss to Egbuka with just under one minute remaining to erase a 20-17 deficit. Mayfield also finished as Tampa Bay's leading rusher, and his quick chemistry with Egbuka bodes well heading into a tough Week 2 road matchup against the Texans on Monday night, Sept. 15.

Murray completed 21 of 29 passes for 163 yards and two touchdowns in Sunday's 20-13 win over the Saints. He added 38 rushing yards on seven carries.

The 28-year-old QB did get sacked five times, but it was otherwise a very sharp performance from Murray in the season opener. Both touchdown passes came in the red zone in the second quarter, as he found Marvin Harrison for a one-yard score before chucking a shovel pass to James Conner for a four-yard TD. Murray threw multiple TD passes only four times in 17 regular-season games in 2024, so this was a very encouraging start to 2025 for the Cardinals' passing game. He figures to be productive again at home Week 2 against the Panthers.

Burrow completed 14 of 23 passes for 113 yards, one touchdown and no interceptions and rushed twice for three yards in Sunday's 17-16 win over the Browns.

Burrow and the Bengals had the ball for only 24:11 and ran just 49 offensive plays. On top of the limited volume, Burrow managed only 5.0 yards per attempt, with his longest completion going for just 20 yards. He did manage to throw a one-yard touchdown to Noah Fant in an otherwise disappointing performance. Burrow should be in for a resurgent showing in Week 2 against Jacksonville.