Brieske (ankle) will begin a rehab assignment at High-A West Michigan on Wednesday, Chris McCosky of The Detroit News reports.

Right ankle inflammation has kept Brieske on the injured list since April 18, and the Tigers will now look to get him a few reps in the minors before he's eligible to return May 3. The 27-year-old has allowed seven runs in just 7.1 innings this season, and he'll likely pitch in middle relief once activated.

Santos (knee) was transferred to the 60-day injured list by Seattle on Tuesday.

Santos is dealing with right knee inflammation. The Mariners needed his 40-man roster spot in order to select Samad Taylor's contract from Triple-A Tacoma.

The Guardians optioned Bolton to Triple-A Columbus on Tuesday, Tim Stebbins of MLB.com reports.

Bolton was in the majors for just one day and yielded three runs over two innings in his lone appearance. He's being sent out in favor of fresh bullpen help.

The Guardians recalled Cantillo from Triple-A Columbus on Tuesday, Tim Stebbins of MLB.com reports.

The left-hander was optioned to Columbus on Monday, but he's eligible to be recalled a day later since Paul Sewald (shoulder) was placed on the injured list. Cantillo has been an effective bullpen piece for Cleveland early this year and has a 2.35 ERA, 1.37 WHIP and 20:8 K:BB across 15.1 innings.

The Guardians placed Sewald on the 15-day injured list Tuesday with a right shoulder strain, Tim Stebbins of MLB.com reports.

Sewald was forced to depart an appearance Monday against the Twins due to the injury and it will cost him at least the next couple weeks of action. The veteran reliever had been roughed up for five runs over 3.2 innings covering his last five outings.

The Blue Jays optioned Schultz to Triple-A Buffalo on Tuesday.

The right-hander was called up by Toronto on April 20 and struck out eight over 4.1 scoreless frames in his MLB debut that day, but he'll head back to Triple-A after giving up three runs across 2.1 innings Sunday at Yankee Stadium. Schultz is likely to get another look in the big leagues at some point this season, but for now he'll return to Buffalo.

The Orioles optioned Strowd to Triple-A Norfolk on Tuesday.

He's clearing out to make room on the roster for Kyle Gibson, who will start Tuesday's game versus the Yankees. Strowd was with the big club for only one day and did not make an appearance.

Williams struck out one batter in a scoreless inning in Monday's 4-3 loss to the Orioles.

Yankees manager Aaron Boone announced Sunday that Williams was being temporarily removed as the team's closer after the right-hander gave up three earned runs in consecutive appearances. Williams got a chance to work in a lower-leverage situation Monday, as New York trailed by one in the eighth inning when he entered the game. He had little trouble dispatching of the three Orioles batters he faced, needing 14 pitches (nine strikes) to retire the side in order. If Williams is able to smooth things out and put together a string of effective outings, he could move back into the closer role in due time.

Wilson is expected to work in bulk relief behind opening pitcher Tyler Gilbert in Tuesday's game against the Brewers in Chicago, Scott Merkin of MLB.com reports.

Gilbert made one-inning starts as an opener this past Friday and Saturday, and he'll likely be in line for a similar workload Tuesday before turning the game over to Wilson. After Martin Perez (shoulder) landed on the injured list April 19, Wilson was called upon to make his first start of the season last Wednesday against the Twins and took a no-decision while giving up one earned run on five hits and three walks over 2.2 innings. He tossed 55 pitches in the start and could push into the 60-to-75 range Tuesday in what's essentially his second turn through the White Sox rotation.

Junis allowed one hit and struck out one over two scoreless innings in Monday's 11-1 loss to the Twins.

Junis, who entered after starter Gavin Williams lasted just two innings, took a comebacker off his left quad in the third inning. He was down for a brief time while trainers assessed the right-hander and was deemed fit to continue. He got out of that inning and set down the side in order in the fourth. Junis has been a useful arm out of the bullpen, posting a 1.93 ERA with just one walk over 14 innings.