Kremer (8-9) took the loss Tuesday, allowing one run on five hits and one walk over eight innings as the Orioles were downed 1-0 by the Mariners. He struck out six.

The right-hander put together one of his best performances of the season, completing eight innings for the first time as he dialed up his seventh quality start of the year on 101 pitches (67 strikes). Seattle squeezed a run across in the top of the first inning, however, and Baltimore's bats couldn't solve George Kirby and the M's bullpen. Kremer hasn't gotten into the win column since the All-Star break, but he hasn't pitched poorly, posting a 3.94 ERA, 1.16 WHIP and 28:9 K:BB over five starts and 32 innings. He'll try to end his winless streak in his next outing, which is scheduled to come on the road this weekend in Houston.

Melton is likely to work as the bulk pitcher for the Tigers in Wednesday's game against the White Sox, Tony Paul of The Detroit News reports.

The Tigers are building in an extra rest day for all five members of their rotation this week, so Melton will be tasked with covering most of the innings Wednesday in what could be a bullpen day. One of the Tigers' top pitching prospects, Melton has had a breakout season in the minors and has been excellent for Detroit after a blowup outing in his big-league debut July 23. In his last three appearances, Melton has a 0.73 ERA, 0.73 WHIP, eight strikeouts and two wins in 12.1 innings. Melton last logged 3.1 innings in a relief appearance Friday, so he should be able to offer the Tigers a decent amount of length in his return to the bump.

Brewers manager Pat Murphy said Tuesday that Misiorowski (tibia) could return from the 15-day injured list to make an abbreviated start Friday in Cincinnati, Hunter Baumgardt of 97.3 The Game reports.

A rehab start for Misiorowski on Friday is also a possibility. The Brewers have revealed their probable pitchers for Saturday (Quinn Priester) and Sunday (Jose Quintana) but are listing Friday as TBA. A decision on where Misiorowski will pitch Friday should be revealed soon. The rookie right-hander is working his way back from a left tibia contusion.

Kirby (8-5) picked up the win in Tuesday's 1-0 victory over the Orioles, allowing three hits over seven scoreless innings. He struck out seven without walking a batter.

The right-hander racked up 32 called or swinging strikes among his 87 pitches (57 total strikes) en route to his fourth straight win, and his eighth quality start of the season. Kirby has gotten into the win column in seven of his last eight outings, delivering a 2.42 ERA, 0.91 WHIP and 54:11 K:BB across 48.1 innings during that red-hot stretch. He'll look to keep rolling in his next trip to the mound, which lines up to come on the road this weekend against the Mets.

Sale (ribs) was charged with one run over two innings of work in his first rehab start with Triple-A Gwinnett on Tuesday.

Sale permitted three hits and two walks while recording a pair of strikeouts, throwing 40 pitches over his two frames. The left-hander averaged 93.9 mph with his four-seamer, which is down one tick from his season average. Per Ken Sugiura of the Atlanta Journal-Constitution, Sale is likely to make two more rehab starts before rejoining the big-league rotation.

Megill (elbow) struck out four over 1.2 scoreless innings in his first rehab start with Double-A Binghamton on Tuesday.

Megill surrendered three hits and a walk but managed to emerge from the outing unscathed, getting his pitch count up to 41. It was the first outing for the right-hander in nearly two months, so it's going to take Megill a while to get built back up. Megill is working his way back from a right elbow sprain.

May (7-8) picked up the win Tuesday against Houston, allowing five hits and one walk with eight strikeouts over six scoreless innings.

May notched his first win with the Red Sox after yielding three runs in 3.2 innings during his Boston debut last week. Tuesday's outing marked May's third scoreless start of the campaign, and he fell one strikeout short of tying his season high. In 113.2 innings this season, May has a 4.67 ERA, 1.35 WHIP and 109:45 K:BB. He's tentatively scheduled to face the Orioles his next time out.

McCullers (finger) will begin a rehab assignment Friday with Triple-A Sugar Land, MLB.com reports.

McCullers threw a bullpen session in Houston on Tuesday after throwing a four-inning simulated game a week earlier. Given the significant ramp-up before his scheduled rehab start, McCullers could be activated from the injured list by late August.

Arrighetti (1-3) took the loss Tuesday against Boston, allowing two runs on one hit and five walks with three strikeouts over five innings.

Arrighetti was hit around by Miami in his first start off the injured list last week and struggled to find the zone Tuesday. The 25-year-old had been sidelined since early April, so it's not too surprising for him to be rusty. That said, he allowed nine runs (seven earned) during his three-start minor-league rehab stint, which doesn't inspire much confidence. He'll look to get back on track in his next start, which is tentatively scheduled to come in Detroit.

Leiter didn't factor into the decision Tuesday against Arizona, allowing one run on four hits and two walks with three strikeouts over five innings.

The only damage against Leiter came in the third inning, when Blaze Alexander clubbed a solo home run. The long ball snapped Leiter's streak of three consecutive starts without allowing a homer. Leiter threw 58 of his 91 pitches for strikes and walked fewer than three batters for the first time in six outings. The 25-year-old will take a 3.94 ERA and 96:54 K:BB into his next start, which is scheduled to come early next week against Kansas City.